Other Blood Group System Quiz

For each blood group system you must know the antigens, antibody class, phase of reactivity in vitro tests, clinical significance, and other important unique charcteristics.

Blood group

Enzyme treatment

Immunoglobulin type

Disease Association

Kell

Antigens: K (Kell), k (Cellano), Kpa, Kpb, Jsa, Jsb

 

No effect

IgG

McLeod phenotype 

Duffy

Fya and Fyb

Dosage effect

Destroys Fya and Fyb

IgG

HTR and HDN

Fy (a-b-) phenotype: resistant to malarial infection caused by Plasmodium vivax

 

Kidd  (Jk)

Jka, Jkb, Jk3

Dosage effect, binds compliment

Enhanced

IgG

HTR and mild HDN

Delayed Hemolytic transfusion reaction (DHTR)

Jk (a–b–) phenotype: resist lysis in 2M Urea

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Other Blood Group System Quiz

 

 

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Category: Bloodbank

1. Which of the following antibody is an IgG biphasic antibody in Donath-Landsteiner antibody test?

 

 

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Category: Bloodbank

2. Which antibody can be neutralized with human breast milk?

 

 

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Category: Bloodbank

3. Which blood group system does Anti-Jsa and Anti-Js b belong to?

 

The genes GYPA codes for glycophorin A for blood group M and N

The genes GYPB codes for glycophorin B for blood group S and s

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Category: Bloodbank

4. Which blood group system is produced by glycophorin A?

 

 

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Category: Bloodbank

5. Which blood group system do K and k antigens belong to?

Rh, Kidd, Lewis, P and I blood group are enhanced by enzymes

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Category: Bloodbank

6. Which antigen(s) is enhanced by enzymes?

 

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Category: Bloodbank

7. What genes are necessary for the production of Leb Antigens?

 

 

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Category: Bloodbank

8. Which antigen has a receptor for Haemophilus influenza?

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Category: Bloodbank

9. Which blood group system is associated with Chronic Granulomatous Disease (CGD)?

 

 

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Category: Bloodbank

10. Which antibody is neutralized by urine to allow detection of other alloantibodies?

The genes GYPA codes for glycophorin A for blood group M and N

The genes GYPB codes for glycophorin B for blood group S and s

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Category: Bloodbank

11. Which blood group system is produced by glycophorin B?

Duffy, MNS and Xga are destroyed by enzymes

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Category: Bloodbank

12. Which antigen is destroyed by enzymes?

 

Anti P is cold reactive antibody; while others are warm reactive antibodies.

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Category: Bloodbank

13. Which antibody does not fit with the others with respect to optimum phase of reactivity?

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Category: Bloodbank

14. Which condition is X- linked and is associated with abnormal RBC morphology, compensated hemolytic anemia, neurological and muscular abnormalities ?

 

 

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Category: Bloodbank

15. Which of the following are antibodies to low-frequency antigens?

Plasma hemoglobin, ammonia, and K+ levels increases

Plasma Na+,  pH and 2,3-BPG levels decreases.

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Category: Bloodbank

16. Which autoantibody specificity is found in patients with infectious mononucleosis?

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Category: Bloodbank

17. Which autoantibody specificity is found in patients with paroxysmal cold hemoglobinuria?

 

 

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Category: Bloodbank

18. Which antibody can be neutralized with pooled plasma to allow detection of other antibodies?

Anti Jka is warm antibody; while others are cold reactive antibodies.

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Category: Bloodbank

19. Which antibody does not fit with the others with respect to optimum phase of reactivity?

 

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Category: Bloodbank

20.

Which antibody is most commonly associated with delayed hemolytic transfusion reactions?

 

MN, Kidd, Duffy are well developed at birth

 

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Category: Bloodbank

21. Which blood group antigen is well developed at birth?

 

 

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Category: Bloodbank

22. Which blood group antigen is located near the RBC membrane and present when S or s is inherited?

Plasma hemoglobin, ammonia, and K+ levels increases

Plasma Na+,  pH and 2,3-BPG levels decreases.

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Category: Bloodbank

23. Which autoantibody is associated with Echinococcus granulosis?

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Category: Uncategorized

24. Which blood group antigen resist lysis in 2M Urea?

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Category: Bloodbank

25. Which autoantibody specificity is found in patients with Mycoplasma pneumonia?

 

 

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Category: Bloodbank

26. Which antigens are strongly expressed on placental tissues?

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Category: Bloodbank

27. Which autoantibody is associated with early abortion?

 

 

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Category: Bloodbank

28. Which blood group system does Anti-Jka and Anti-Jkb belong to?

 

 

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Category: Bloodbank

29. Which antibody is neutralized in vitro by Lewis substance?

 

 

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Category: Bloodbank

30. What is biphasic hemolysin?

Kidd, Duffy, MNS blood groups are known for showing dosage

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Category: Bloodbank

31. Which of the following blood group antigens are known for showing dosage?

 

 

 

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Category: Bloodbank

32. The antibody to this high prevalence antigen appears shiny and refractile under the microscope.

Plasma hemoglobin, ammonia, and K+ levels increases

Plasma Na+,  pH and 2,3-BPG levels decreases.

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Category: Bloodbank

33. Which blood group system is associated with McLeod phenotype?

 

 

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Category: Bloodbank

34. Which blood group system do Anti-Fya and Anti-Fybelong to?

 

 

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Category: Bloodbank

35. Antigen that shows dosage must be rule out with?

 

 

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Category: Bloodbank

36. Which of the following are antibodies to high frequency antigens?

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Category: Bloodbank

37. Which blood group system is associated with resistance to P. vivax malaria?

Anti-P1  is easily inhibited with P1 substance(Hydatid cyst fluid)

 

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Category: Bloodbank

38. Which antibody is neutralized by hydatid cyst fluid to allow detection of other antibodies?

MN, Kidd, Duffy are well developed at birth while P and Lutheran blood group system are poorly developed at birth

 

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Category: Bloodbank

39. Which blood group antigen is poorly developed at birth?

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