Other Blood Group System Quiz

For each blood group system you must know the antigens, antibody class, phase of reactivity in vitro tests, clinical significance, and other important unique charcteristics.

Blood group

Enzyme treatment

Immunoglobulin type

Disease Association

Kell

Antigens: K (Kell), k (Cellano), Kpa, Kpb, Jsa, Jsb

 

No effect

IgG

McLeod phenotype 

Duffy

Fya and Fyb

Dosage effect

Destroys Fya and Fyb

IgG

HTR and HDN

Fy (a-b-) phenotype: resistant to malarial infection caused by Plasmodium vivax

 

Kidd  (Jk)

Jka, Jkb, Jk3

Dosage effect, binds compliment

Enhanced

IgG

HTR and mild HDN

Delayed Hemolytic transfusion reaction (DHTR)

Jk (a–b–) phenotype: resist lysis in 2M Urea

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Other Blood Group System Quiz

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1. Which blood group antigen resist lysis in 2M Urea?

Duffy, MNS and Xga are destroyed by enzymes

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2. Which antigen is destroyed by enzymes?

 

 

 

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3. Which antibody can be neutralized with pooled plasma to allow detection of other antibodies?

 

 

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4. Which of the following are antibodies to low-frequency antigens?

 

 

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5. Antigen that shows dosage must be rule out with?

 

 

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6. Which of the following are antibodies to high frequency antigens?

 

 

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7. What is biphasic hemolysin?

 

 

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Category: Bloodbank

8. Which antigen has a receptor for Haemophilus influenza?

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9. Which blood group system is associated with resistance to P. vivax malaria?

Anti P is cold reactive antibody; while others are warm reactive antibodies.

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10. Which antibody does not fit with the others with respect to optimum phase of reactivity?

 

 

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11. Which blood group system does Anti-Jka and Anti-Jkb belong to?

 

 

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12. Which blood group antigen is located near the RBC membrane and present when S or s is inherited?

 

 

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13. Which of the following antibody is an IgG biphasic antibody in Donath-Landsteiner antibody test?

 

The genes GYPA codes for glycophorin A for blood group M and N

The genes GYPB codes for glycophorin B for blood group S and s

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14. Which blood group system is produced by glycophorin A?

Anti-P1  is easily inhibited with P1 substance(Hydatid cyst fluid)

 

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15. Which antibody is neutralized by hydatid cyst fluid to allow detection of other antibodies?

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16. Which autoantibody specificity is found in patients with Mycoplasma pneumonia?

 

 

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17. Which blood group system do Anti-Fya and Anti-Fybelong to?

Anti Jka is warm antibody; while others are cold reactive antibodies.

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18. Which antibody does not fit with the others with respect to optimum phase of reactivity?

 

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19. Which autoantibody is associated with early abortion?

 

 

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20. Which antibody can be neutralized with human breast milk?

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21. Which autoantibody specificity is found in patients with paroxysmal cold hemoglobinuria?

 

 

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22. Which blood group system does Anti-Jsa and Anti-Js b belong to?

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23. Which condition is X- linked and is associated with abnormal RBC morphology, compensated hemolytic anemia, neurological and muscular abnormalities ?

Kidd, Duffy, MNS blood groups are known for showing dosage

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Category: Bloodbank

24. Which of the following blood group antigens are known for showing dosage?

 

 

 

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25. The antibody to this high prevalence antigen appears shiny and refractile under the microscope.

 

 

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26. Which antigens are strongly expressed on placental tissues?

MN, Kidd, Duffy are well developed at birth while P and Lutheran blood group system are poorly developed at birth

 

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27. Which blood group antigen is poorly developed at birth?

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28. Which blood group system is associated with Chronic Granulomatous Disease (CGD)?

Plasma hemoglobin, ammonia, and K+ levels increases

Plasma Na+,  pH and 2,3-BPG levels decreases.

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29. Which autoantibody is associated with Echinococcus granulosis?

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30.

Which antibody is most commonly associated with delayed hemolytic transfusion reactions?

 

 

 

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31. Which blood group system do K and k antigens belong to?

 

 

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32. Which antibody is neutralized by urine to allow detection of other alloantibodies?

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33. What genes are necessary for the production of Leb Antigens?

The genes GYPA codes for glycophorin A for blood group M and N

The genes GYPB codes for glycophorin B for blood group S and s

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34. Which blood group system is produced by glycophorin B?

Plasma hemoglobin, ammonia, and K+ levels increases

Plasma Na+,  pH and 2,3-BPG levels decreases.

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35. Which autoantibody specificity is found in patients with infectious mononucleosis?

MN, Kidd, Duffy are well developed at birth

 

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36. Which blood group antigen is well developed at birth?

Plasma hemoglobin, ammonia, and K+ levels increases

Plasma Na+,  pH and 2,3-BPG levels decreases.

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37. Which blood group system is associated with McLeod phenotype?

Rh, Kidd, Lewis, P and I blood group are enhanced by enzymes

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38. Which antigen(s) is enhanced by enzymes?

 

 

 

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Category: Bloodbank

39. Which antibody is neutralized in vitro by Lewis substance?

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