Other Blood Group System Quiz

For each blood group system you must know the antigens, antibody class, phase of reactivity in vitro tests, clinical significance, and other important unique charcteristics.

Blood group

Enzyme treatment

Immunoglobulin type

Disease Association

Kell

Antigens: K (Kell), k (Cellano), Kpa, Kpb, Jsa, Jsb

 

No effect

IgG

McLeod phenotype 

Duffy

Fya and Fyb

Dosage effect

Destroys Fya and Fyb

IgG

HTR and HDN

Fy (a-b-) phenotype: resistant to malarial infection caused by Plasmodium vivax

 

Kidd  (Jk)

Jka, Jkb, Jk3

Dosage effect, binds compliment

Enhanced

IgG

HTR and mild HDN

Delayed Hemolytic transfusion reaction (DHTR)

Jk (a–b–) phenotype: resist lysis in 2M Urea

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Other Blood Group System Quiz

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Category: Bloodbank

1. Which autoantibody specificity is found in patients with Mycoplasma pneumonia?

 

 

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Category: Bloodbank

2. Which of the following are antibodies to low-frequency antigens?

 

 

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Category: Bloodbank

3. What is biphasic hemolysin?

Anti P is cold reactive antibody; while others are warm reactive antibodies.

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Category: Bloodbank

4. Which antibody does not fit with the others with respect to optimum phase of reactivity?

 

 

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Category: Bloodbank

5. Which antigens are strongly expressed on placental tissues?

 

 

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Category: Bloodbank

6. Which of the following are antibodies to high frequency antigens?

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Category: Bloodbank

7. Which blood group system is associated with resistance to P. vivax malaria?

 

 

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Category: Bloodbank

8. Antigen that shows dosage must be rule out with?

 

 

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Category: Bloodbank

9. The antibody to this high prevalence antigen appears shiny and refractile under the microscope.

Anti Jka is warm antibody; while others are cold reactive antibodies.

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Category: Bloodbank

10. Which antibody does not fit with the others with respect to optimum phase of reactivity?

 

 

 

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Category: Bloodbank

11. Which blood group system does Anti-Jsa and Anti-Js b belong to?

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Category: Uncategorized

12. Which blood group antigen resist lysis in 2M Urea?

Kidd, Duffy, MNS blood groups are known for showing dosage

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Category: Bloodbank

13. Which of the following blood group antigens are known for showing dosage?

 

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Category: Bloodbank

14. Which autoantibody is associated with early abortion?

 

 

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Category: Bloodbank

15. Which of the following antibody is an IgG biphasic antibody in Donath-Landsteiner antibody test?

MN, Kidd, Duffy are well developed at birth

 

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Category: Bloodbank

16. Which blood group antigen is well developed at birth?

 

 

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Category: Bloodbank

17. Which blood group system do Anti-Fya and Anti-Fybelong to?

Plasma hemoglobin, ammonia, and K+ levels increases

Plasma Na+,  pH and 2,3-BPG levels decreases.

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Category: Bloodbank

18. Which blood group system is associated with McLeod phenotype?

Plasma hemoglobin, ammonia, and K+ levels increases

Plasma Na+,  pH and 2,3-BPG levels decreases.

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Category: Bloodbank

19. Which autoantibody is associated with Echinococcus granulosis?

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Category: Bloodbank

20. What genes are necessary for the production of Leb Antigens?

Anti-P1  is easily inhibited with P1 substance(Hydatid cyst fluid)

 

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Category: Bloodbank

21. Which antibody is neutralized by hydatid cyst fluid to allow detection of other antibodies?

 

 

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Category: Bloodbank

22. Which antibody is neutralized in vitro by Lewis substance?

 

 

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Category: Bloodbank

23. Which blood group antigen is located near the RBC membrane and present when S or s is inherited?

Rh, Kidd, Lewis, P and I blood group are enhanced by enzymes

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Category: Bloodbank

24. Which antigen(s) is enhanced by enzymes?

 

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Category: Bloodbank

25.

Which antibody is most commonly associated with delayed hemolytic transfusion reactions?

 

 

The genes GYPA codes for glycophorin A for blood group M and N

The genes GYPB codes for glycophorin B for blood group S and s

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Category: Bloodbank

26. Which blood group system is produced by glycophorin A?

Plasma hemoglobin, ammonia, and K+ levels increases

Plasma Na+,  pH and 2,3-BPG levels decreases.

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Category: Bloodbank

27. Which autoantibody specificity is found in patients with infectious mononucleosis?

 

 

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Category: Bloodbank

28. Which blood group system do K and k antigens belong to?

Duffy, MNS and Xga are destroyed by enzymes

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Category: Bloodbank

29. Which antigen is destroyed by enzymes?

 

The genes GYPA codes for glycophorin A for blood group M and N

The genes GYPB codes for glycophorin B for blood group S and s

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Category: Bloodbank

30. Which blood group system is produced by glycophorin B?

 

 

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Category: Bloodbank

31. Which antibody can be neutralized with human breast milk?

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Category: Bloodbank

32. Which blood group system is associated with Chronic Granulomatous Disease (CGD)?

MN, Kidd, Duffy are well developed at birth while P and Lutheran blood group system are poorly developed at birth

 

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Category: Bloodbank

33. Which blood group antigen is poorly developed at birth?

 

 

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Category: Bloodbank

34. Which antigen has a receptor for Haemophilus influenza?

 

 

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Category: Bloodbank

35. Which antibody can be neutralized with pooled plasma to allow detection of other antibodies?

 

 

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Category: Bloodbank

36. Which antibody is neutralized by urine to allow detection of other alloantibodies?

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Category: Bloodbank

37. Which autoantibody specificity is found in patients with paroxysmal cold hemoglobinuria?

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Category: Bloodbank

38. Which condition is X- linked and is associated with abnormal RBC morphology, compensated hemolytic anemia, neurological and muscular abnormalities ?

 

 

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Category: Bloodbank

39. Which blood group system does Anti-Jka and Anti-Jkb belong to?

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