224 Questions; Clinical Chemistry Question Banks

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224 Questions; Clinical Chemistry Question Banks

224 Multiple choice questions to help you prepare for the ASCP exam or quizzes.

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1. What does decreased pH and ctCO2 with normal PCO2 indicate? 

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2. Which hormone Stimulates secretion of prolactin 

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3. Which ions is the major cation of intracellular fluid?

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4. Which enzyme is elevated in biliary tract obstruction? 

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5. Calculate LDL cholesterol given a total cholesterol of 220mg/dl,  65mg/dl of HDL and triglyceride 200 mg/dl 

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6. Which lipoprotein function has an antiatherogenic effect?

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7. Which blood protein is most responsible for osmotic pressure?

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8. What is the primary male sex hormone?

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9. The biuret method for the determination of protein concentrations measures the amount of?

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10. Which of the following condition causes respiratory acidosis?

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11. What type of diabetes is associated with obesity and a sedentary lifestyle? 

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12. Of the following blood glucose levels, which would you expect to result  in glucose in the urine? 

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13. Which type of lipid consists of one glycerol molecule and two fatty acid  molecules attached via ester bonds?

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14. Which one of the following is the most specific biochemical marker of  myocardial infarction? 

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15. What is the presence of glucose in urine called? 

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16. What is another name for Vitamin B12?

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17. Which of the following oncofetal antigen is associated with Down syndrome?

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18. Which disorder is associated with Vitamin B12 deficiency?

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19. What is the major waste product of purine catabolism? 

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20. Which one of the following biochemical marker is used for assessing  heart failure? 

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21. Which hormone controls water homeostasis?

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22. What are macromolecules made of amino acids linked to another by peptide bond called?

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23. Given the following information for an average-size adult, calculate creatinine clearance. Urine creatinine—130 mg/dL Plasma creatinine—1.4 mg/dL Urine volume for 24 hours—1620 ml

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24. What is the major protein found in Low-density lipoprotein (LDL)? 

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25. Which condition is caused by deficient secretion of bilirubin into the bile canaliculi?

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26. What is renal threshold for glucose?

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27. Which of the following is a sialylated Lewis blood group antigen associated with colorectal carcinoma?

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28. Excessive galactose in blood and excretion in urine is called

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29. Which lipoprotein are recycled chylomicron and VLDL molecules?

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30. Which protein binds to free hemoglobin?

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31. What form are carbohydrates stored in the liver and skeletal muscles?

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32. Which cardiac enzyme is elevated in central nervous system disorders? 

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33. What are positively charged ions called?

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34. Which of the following vitamin is water-soluble?

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35. Rickets is caused by a deficiency in which of the following?

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36. What is a fasting blood glucose level >100 mg/dL called?

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37. What is the major protein found in High-density lipoprotein (HDL)? 

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38. What type of diabetes is more prone to ketoacidosis? 

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39. In which condition would you expect an increased level of alpha-1-antitrypsin and C-reactive protein (CRP)?

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40. Which of the following hormone stimulates lipolysis and  gluconeogenesis?

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41. What analyte is measured using the Jaffe reaction?

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42. Which of the following hormones does not promote an increase in blood  glucose levels? 

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43. Which of the following tumor marker is used for detecting recurrence of breast cancer?

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44. Which ions is the major cation of extracellular fluid?

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45. What is another name for Vitamin B1?

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46. Where is insulin produced?

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47.  Decreased alpha-1-fetoprotein level in maternal serum is expected in which of the following disorder?

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48. Which of the following lipid act as a precursor of bile acids, Vitamin D and  steroids?

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49. Which disorder is characterized by buildup of unconjugated bilirubin in the blood due to deficiency of UDPglycuronyltransferase?

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50. Which of the following protein is used to predict the risk of premature birth?

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51. Which of the following protein is elevated in the amniotic fluid in neural tube defects?

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52.  In gout, which of the following compound deposits in joints and other body tissues? 

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53. Triglycerides are transported through the body by 

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54. Which element distinguishes proteins from carbohydrate and lipid compounds?

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55. Cushing syndrome causes?  

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56. Which of the following condition causes metabolic acidosis?

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57. In metabolic acidosis, total carbon dioxide is

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58. Which analyte should be placed on ice immediately after draw?

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59. What is another name for Vitamin C?

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60. Which hormone inhibits release of prolactin?

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61. Osteoporosis is caused by a deficiency in which of the following?

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62. What is the major fat in adipose tissues? 

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63. What is the process of breaking down glucose to form pyruvate  molecules?

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64. Which of the following is an oncofetal antigen that is elevated in neural defect?

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65. Which of the following carbohydrates is a polysaccharide? 

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66. What is the process of formation of glycogen from glucose called? 

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67. Which hormone inhibits the secretion of thyroid-stimulating hormone?

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68. What is the normal range of sodium?

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69. What vitamin helps regulate calcium?

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70. Elevated levels of which lipoprotein is associated with decreased risk for  coronary artery disease?

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71. What is the presence of glucose in urine called? 

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72. Which of the following helps regulate calcium?

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73. Which of the following protein is found in urine of a patient with multiple myeloma?

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74. Which glucose method is considered to be the reference method? 

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75. Decreased levels of which lipoprotein is associated with increased risk  for coronary artery disease?

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76. Which exhibit diurnal variation, with highest levels in the morning?

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77. Which hormone regulates salt balance?

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78. Convert 20 mg/dL of urea nitrogen to urea. 

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79. In what condition would an increased level of serum albumin be expected?

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80. Which lipoprotein is known as "bad cholesterol"?

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81. Which analyte will be falsely elevated due to hemolysis?

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82. Which protein transports iron?

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83. Which hormone increases blood glucose by stimulating glycogenolysis? 

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84. Which lipoprotein is known as "Good cholesterol"?

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85. What is a fasting blood glucose level >100 mg/dL called? 

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86. Which of the following condition is associated with (XXY)?

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87. In which condition will antidiuretic hormone level decrease?

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88. Which hormones stimulates uterine contractions during childbirth?

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89. Which of the following electrolyte is an important buffer system of blood?

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90. Which of the following vitamin is fat-soluble?

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91. What is another name for Vitamin B6?

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92.  What is the primary female sex hormone?

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93. Which disorder is associated with excess cortisol production?

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94. Which ions is the major anion of extracellular fluid?

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95. In what form is glucose stored in muscle and liver?

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96. What is another name for Vitamin B2?

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97. Which marker is used as a predictor for cardiovascular risk; increased  levels seen in inflammation? 

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98. Which hormone increases blood glucose by stimulating glycogenolysis?

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99. Which enzyme is elevated in Paget disease?

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100. What hormone increases osmolality?

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101. Triglycerides are transported through the body by 

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102. Which hormone inhibits the release of glucose from the liver?

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103. Which disorder is associated with Niacin deficiency? 

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104. Which of the following glycoprotein are markers for ovarian and endometrial cancer?

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105. Which lipoprotein is the largest and have lowest density? 

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106. Which substance is released when serum calcium level increases?

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107. Which of the following condition will cause hyponatremia?

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108. Which of the following vitamin is water-soluble?

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109. Which of the following is a tissue-specific marker used to detect prostate cancer?

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110. Which hormones are secreted by the anterior Pituitary Gland?

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111. What does normal ctCO2, increased pH with decreased PCO2 indicate? 

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112. Which of the following vitamin is fat-soluble?

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113. High-sensitivity CRP (hs-CRP) of 3.0 mg/L is indicative of  

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114. Which lipoprotein is known as "bad cholesterol"?

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115. Which of the following vitamin is water-soluble?

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116. Which of the following is an oncofetal antigen that is elevated in colorectal carcinoma?

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117. Which test is used to detect pregnancy?

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118. What type of diabetes is associated with obesity and sedentary lifestyle?

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119. What is the three-dimensional shape of a protein called?

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120. What is the major constituents of cell membranes and outer shells of  lipoprotein molecules? 

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121. Which enzyme is elevated in Mumps? 

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122. Where is insulin produced? 

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123. In metabolic alkalosis, bicarbonate is

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124. Which of the following ion is an anion 

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125. Which enzyme deficiency will result in increased sensitivity to  certain muscle relaxant drugs used during surgery? 

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126. In diabetic ketoacidosis, total carbon dioxide is

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127. What is end product of glucose metabolism in anaerobic condition?

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128. What is the renal threshold for glucose? 

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129. Which lipoprotein is the largest and have lowest density? 

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130. An onset of diabetes mellitus during pregnancy is known as 

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131. Which of the following glycoprotein is elevated in trophoblastic tumors?

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132. What does increased ctCO2 and pH with normal PCO2 indicate? 

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133. In the diacetyl method, what does diacetyl react with to form a yellow product?

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134. A colored stool is seen in

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135. In what condition would decreased level of alpha-1-antitrypsin be expected?

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136. The structure formed by the sequence of amino acids within a polypeptide chain is?

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137. Decreased level of haptoglobin is indicative of?

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138. What molecule is formed from one molecule of glycerol and three fatty  acid molecules? 

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139. Which hormone increases blood glucose during stress? 

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140. What molecule is formed from one molecule of glycerol and three fatty acid molecules?

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141. What is the final product of Epinephrine metabolism is?.

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142. The Kjeldahl tecnique for the determination of total proteim measures the amount of?

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143. What is the process by which glycogen is broken down to glucose? 

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144. Which hormone stimulates stimulates production of testosterone?

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145. What color does biuret turn when protein is present?

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146. Which enzyme is useful in forensic cases involving rape?

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147. What hormone helps regulate Phosphorus?

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148. Which lipoprotein is the primary carrier of cholesterol?

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149. What form are carbohydrates stored in the liver and skeletal muscles?

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150. Which type of diabetes is characterized by relative insulin resistance?

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151. It is an indicator of arterial inflammation.  

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152. Which disorder is associated with Vitamin B2 deficiency?

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153. Which enzyme deficiency is associated with hemolytic anemia after  ingestion of fava beans? 

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154. Elevated levels of which lipoprotein is associated with increased risk for  atherosclerosis?

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155. Which of the following immunoglobin is increased in allergies, asthma, and parasitic infections?

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156. Hemorrhagic disease is associated with deficiency of which of the following vitamin?

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157. Which protein activates lecithincholesterol acyltransferase  (LCAT) and removes free cholesterol from extrahepatic tissues? 

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158. What type of diabetes is more prone to ketoacidosis?

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159. Which of the following condition causes respiratory alkalosis?

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160. Which of the following hormone stimulates lipolysis and  gluconeogenesis?

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161. Which hormone inhibits the release of glucose from the liver?

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162. Scurvy is caused by a deficiency in which of the following?

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163. What is the major fat in adipose tissues? 

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164. Which of the following hormone is catecholamine?

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165. What hormone helps regulate calcium?

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166. What is the process of breaking down glucose to form pyruvate  molecules?

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167. Which enzyme is elevated in patient with alcoholic cirrhosis? 

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168. Which enzyme is decreased in insecticide poisonings? 

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169. Excessive galactose in blood and excretion in urine is called

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170. Which lipoprotein gives serum a turbid appearance? 

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171. What is the major constituents of cell membranes and outer shells of  lipoprotein molecules?