224 Questions; Clinical Chemistry Question Banks

1. What does decreased pH and ctCO2 with normal PCO2 indicate? 

2. Which hormone Stimulates secretion of prolactin 

3. Which ions is the major cation of intracellular fluid?

4. Which enzyme is elevated in biliary tract obstruction? 

5. Calculate LDL cholesterol given a total cholesterol of 220mg/dl,  65mg/dl of HDL and triglyceride 200 mg/dl 

6. Which lipoprotein function has an antiatherogenic effect?

7. Which blood protein is most responsible for osmotic pressure?

8. What is the primary male sex hormone?

9. The biuret method for the determination of protein concentrations measures the amount of?

10. Which of the following condition causes respiratory acidosis?

11. What type of diabetes is associated with obesity and a sedentary lifestyle? 

12. Of the following blood glucose levels, which would you expect to result  in glucose in the urine? 

13. Which type of lipid consists of one glycerol molecule and two fatty acid  molecules attached via ester bonds?

14. Which one of the following is the most specific biochemical marker of  myocardial infarction? 

15. What is the presence of glucose in urine called? 

16. What is another name for Vitamin B12?

17. Which of the following oncofetal antigen is associated with Down syndrome?

18. Which disorder is associated with Vitamin B12 deficiency?

19. What is the major waste product of purine catabolism? 

20. Which one of the following biochemical marker is used for assessing  heart failure? 

21. Which hormone controls water homeostasis?

22. What are macromolecules made of amino acids linked to another by peptide bond called?

23. Given the following information for an average-size adult, calculate creatinine clearance. Urine creatinine—130 mg/dL Plasma creatinine—1.4 mg/dL Urine volume for 24 hours—1620 ml

24. What is the major protein found in Low-density lipoprotein (LDL)? 

25. Which condition is caused by deficient secretion of bilirubin into the bile canaliculi?

26. What is renal threshold for glucose?

27. Which of the following is a sialylated Lewis blood group antigen associated with colorectal carcinoma?

28. Excessive galactose in blood and excretion in urine is called

29. Which lipoprotein are recycled chylomicron and VLDL molecules?

30. Which protein binds to free hemoglobin?

31. What form are carbohydrates stored in the liver and skeletal muscles?

32. Which cardiac enzyme is elevated in central nervous system disorders? 

33. What are positively charged ions called?

34. Which of the following vitamin is water-soluble?

35. Rickets is caused by a deficiency in which of the following?

36. What is a fasting blood glucose level >100 mg/dL called?

37. What is the major protein found in High-density lipoprotein (HDL)? 

38. What type of diabetes is more prone to ketoacidosis? 

39. In which condition would you expect an increased level of alpha-1-antitrypsin and C-reactive protein (CRP)?

40. Which of the following hormone stimulates lipolysis and  gluconeogenesis?

41. What analyte is measured using the Jaffe reaction?

42. Which of the following hormones does not promote an increase in blood  glucose levels? 

43. Which of the following tumor marker is used for detecting recurrence of breast cancer?

44. Which ions is the major cation of extracellular fluid?

45. What is another name for Vitamin B1?

46. Where is insulin produced?

47.  Decreased alpha-1-fetoprotein level in maternal serum is expected in which of the following disorder?

48. Which of the following lipid act as a precursor of bile acids, Vitamin D and  steroids?

49. Which disorder is characterized by buildup of unconjugated bilirubin in the blood due to deficiency of UDPglycuronyltransferase?

50. Which of the following protein is used to predict the risk of premature birth?

51. Which of the following protein is elevated in the amniotic fluid in neural tube defects?

52.  In gout, which of the following compound deposits in joints and other body tissues? 

53. Triglycerides are transported through the body by 

54. Which element distinguishes proteins from carbohydrate and lipid compounds?

55. Cushing syndrome causes?  

56. Which of the following condition causes metabolic acidosis?

57. In metabolic acidosis, total carbon dioxide is

58. Which analyte should be placed on ice immediately after draw?

59. What is another name for Vitamin C?

60. Which hormone inhibits release of prolactin?

61. Osteoporosis is caused by a deficiency in which of the following?

62. What is the major fat in adipose tissues? 

63. What is the process of breaking down glucose to form pyruvate  molecules?

64. Which of the following is an oncofetal antigen that is elevated in neural defect?

65. Which of the following carbohydrates is a polysaccharide? 

66. What is the process of formation of glycogen from glucose called? 

67. Which hormone inhibits the secretion of thyroid-stimulating hormone?

68. What is the normal range of sodium?

69. What vitamin helps regulate calcium?

70. Elevated levels of which lipoprotein is associated with decreased risk for  coronary artery disease?

71. What is the presence of glucose in urine called? 

72. Which of the following helps regulate calcium?

73. Which of the following protein is found in urine of a patient with multiple myeloma?

74. Which glucose method is considered to be the reference method? 

75. Decreased levels of which lipoprotein is associated with increased risk  for coronary artery disease?

76. Which exhibit diurnal variation, with highest levels in the morning?

77. Which hormone regulates salt balance?

78. Convert 20 mg/dL of urea nitrogen to urea. 

79. In what condition would an increased level of serum albumin be expected?

80. Which lipoprotein is known as "bad cholesterol"?

81. Which analyte will be falsely elevated due to hemolysis?

82. Which protein transports iron?

83. Which hormone increases blood glucose by stimulating glycogenolysis? 

84. Which lipoprotein is known as "Good cholesterol"?

85. What is a fasting blood glucose level >100 mg/dL called? 

86. Which of the following condition is associated with (XXY)?

87. In which condition will antidiuretic hormone level decrease?

88. Which hormones stimulates uterine contractions during childbirth?

89. Which of the following electrolyte is an important buffer system of blood?

90. Which of the following vitamin is fat-soluble?

91. What is another name for Vitamin B6?

92.  What is the primary female sex hormone?

93. Which disorder is associated with excess cortisol production?

94. Which ions is the major anion of extracellular fluid?

95. In what form is glucose stored in muscle and liver?

96. What is another name for Vitamin B2?

97. Which marker is used as a predictor for cardiovascular risk; increased  levels seen in inflammation? 

98. Which hormone increases blood glucose by stimulating glycogenolysis?

99. Which enzyme is elevated in Paget disease?

100. What hormone increases osmolality?

101. Triglycerides are transported through the body by 

102. Which hormone inhibits the release of glucose from the liver?

103. Which disorder is associated with Niacin deficiency? 

104. Which of the following glycoprotein are markers for ovarian and endometrial cancer?

105. Which lipoprotein is the largest and have lowest density? 

106. Which substance is released when serum calcium level increases?

107. Which of the following condition will cause hyponatremia?

108. Which of the following vitamin is water-soluble?

109. Which of the following is a tissue-specific marker used to detect prostate cancer?

110. Which hormones are secreted by the anterior Pituitary Gland?

111. What does normal ctCO2, increased pH with decreased PCO2 indicate? 

112. Which of the following vitamin is fat-soluble?

113. High-sensitivity CRP (hs-CRP) of 3.0 mg/L is indicative of  

114. Which lipoprotein is known as "bad cholesterol"?

115. Which of the following vitamin is water-soluble?

116. Which of the following is an oncofetal antigen that is elevated in colorectal carcinoma?

117. Which test is used to detect pregnancy?

118. What type of diabetes is associated with obesity and sedentary lifestyle?

119. What is the three-dimensional shape of a protein called?

120. What is the major constituents of cell membranes and outer shells of  lipoprotein molecules? 

121. Which enzyme is elevated in Mumps? 

122. Where is insulin produced? 

123. In metabolic alkalosis, bicarbonate is

124. Which of the following ion is an anion 

125. Which enzyme deficiency will result in increased sensitivity to  certain muscle relaxant drugs used during surgery? 

126. In diabetic ketoacidosis, total carbon dioxide is

127. What is end product of glucose metabolism in anaerobic condition?

128. What is the renal threshold for glucose? 

129. Which lipoprotein is the largest and have lowest density? 

130. An onset of diabetes mellitus during pregnancy is known as 

131. Which of the following glycoprotein is elevated in trophoblastic tumors?

132. What does increased ctCO2 and pH with normal PCO2 indicate? 

133. In the diacetyl method, what does diacetyl react with to form a yellow product?

134. A colored stool is seen in

135. In what condition would decreased level of alpha-1-antitrypsin be expected?

136. The structure formed by the sequence of amino acids within a polypeptide chain is?

137. Decreased level of haptoglobin is indicative of?

138. What molecule is formed from one molecule of glycerol and three fatty  acid molecules? 

139. Which hormone increases blood glucose during stress? 

140. What molecule is formed from one molecule of glycerol and three fatty acid molecules?

141. What is the final product of Epinephrine metabolism is?.

142. The Kjeldahl tecnique for the determination of total proteim measures the amount of?

143. What is the process by which glycogen is broken down to glucose? 

144. Which hormone stimulates stimulates production of testosterone?

145. What color does biuret turn when protein is present?

146. Which enzyme is useful in forensic cases involving rape?

147. What hormone helps regulate Phosphorus?

148. Which lipoprotein is the primary carrier of cholesterol?

149. What form are carbohydrates stored in the liver and skeletal muscles?

150. Which type of diabetes is characterized by relative insulin resistance?

151. It is an indicator of arterial inflammation.  

152. Which disorder is associated with Vitamin B2 deficiency?

153. Which enzyme deficiency is associated with hemolytic anemia after  ingestion of fava beans? 

154. Elevated levels of which lipoprotein is associated with increased risk for  atherosclerosis?

155. Which of the following immunoglobin is increased in allergies, asthma, and parasitic infections?

156. Hemorrhagic disease is associated with deficiency of which of the following vitamin?

157. Which protein activates lecithincholesterol acyltransferase  (LCAT) and removes free cholesterol from extrahepatic tissues? 

158. What type of diabetes is more prone to ketoacidosis?

159. Which of the following condition causes respiratory alkalosis?

160. Which of the following hormone stimulates lipolysis and  gluconeogenesis?

161. Which hormone inhibits the release of glucose from the liver?

162. Scurvy is caused by a deficiency in which of the following?

163. What is the major fat in adipose tissues? 

164. Which of the following hormone is catecholamine?

165. What hormone helps regulate calcium?

166. What is the process of breaking down glucose to form pyruvate  molecules?

167. Which enzyme is elevated in patient with alcoholic cirrhosis? 

168. Which enzyme is decreased in insecticide poisonings? 

169. Excessive galactose in blood and excretion in urine is called

170. Which lipoprotein gives serum a turbid appearance? 

171. What is the major constituents of cell membranes and outer shells of  lipoprotein molecules?