224 Questions; Clinical Chemistry Question Banks

1. Which of the following protein is elevated in the amniotic fluid in neural tube defects?

2. Which type of diabetes is characterized by relative insulin resistance? 

3. What type of diabetes is more prone to ketoacidosis? 

4. Which analyte will be falsely elevated due to hemolysis?

5. Which marker is used as a predictor for cardiovascular risk; increased  levels seen in inflammation? 

6. A waste product of muscle contraction that is formed from phosphocreatine is

7. What molecule is formed from one molecule of glycerol and three fatty acid molecules?

8. Which condition is caused by deficient secretion of bilirubin into the bile canaliculi?

9. In which condition would you expect an increased level of alpha-1-antitrypsin and C-reactive protein (CRP)?

10. Which cardiac enzyme is elevated in central nervous system disorders? 

11. Which of the following hormone stimulates lipolysis and  gluconeogenesis?

12. What is the final product of Epinephrine metabolism is?.

13. Which of the following is a sialylated Lewis blood group antigen associated with colorectal carcinoma?

14. What type of diabetes is more prone to ketoacidosis?

15. In metabolic acidosis, a decreased pH triggers 

16. What is the presence of glucose in urine called? 

17. What vitamin helps regulate calcium?

18. What is the major fat in adipose tissues? 

19. Elevated levels of which lipoprotein is associated with decreased risk for  coronary artery disease?

20. In diabetic ketoacidosis, total carbon dioxide is

21. Which of the following carbohydrates is a polysaccharide? 

22. Which of the following lipid act as a precursor of bile acids, Vitamin D and  steroids?

23. Which hormone Stimulates secretion of prolactin 

24. Which of the following conditions causes Hypocalcemia?

25.  The Kjeldahl technique for the determination of serum total protein measures the amount of?

26. Which ions is the major anion of extracellular fluid?

27. Which lipoprotein is the primary carrier of cholesterol?

28. Which lipoprotein is known as "Good cholesterol"?

29. Which test is used to assess the average plasma glucose level that an  individual maintained during a previous 2- to 3-month period? 

30. Rickets is caused by a deficiency in which of the following?

31. Elevated levels of which lipoprotein is associated with increased risk for  atherosclerosis?

32. An onset of diabetes mellitus during pregnancy is known as 

33. Which of the following ion is a cation 

34. What is the measure of the number of dissolved particles in solution expressed as osmoles per kilogram of water?

35. Which of the following condition causes respiratory acidosis?

36. What protein has the highest concentration in the plasma?

37. What is a fasting blood glucose level >100 mg/dL called?

38.  Decreased alpha-1-fetoprotein level in maternal serum is expected in which of the following disorder?

39. Which of the following hormones does not promote an increase in blood  glucose levels? 

40. Which of the following condition causes metabolic acidosis?

41. What is the process of breaking down glucose to form pyruvate  molecules?

42. What analyte is measured using the Jaffe reaction?

43. Which of the following is an oncofetal antigen that is elevated in neural defect?

44.  What is the primary female sex hormone?

45. Which of the following vitamin is fat-soluble?

46. What is renal threshold for glucose?

47. What is the process by which glycogen is broken down to glucose?

48. Which of the following condition will cause hyponatremia?

49. Which glucose method is considered to be the reference method? 

50. Which hormones secreted by the anterior pituitary raises blood glucose  levels?

51. What is the process by which glucose is formed from  noncarbohydrate sources?

52. The Kjeldahl tecnique for the determination of total proteim measures the amount of?

53. What hormone helps regulate calcium?

54. In the diacetyl method, what does diacetyl react with to form a yellow product?

55. Which enzyme is elevated in patient with alcoholic cirrhosis? 

56. What is the primary male sex hormone?

57. It is an indicator of arterial inflammation.  

58. Which lipoprotein are recycled chylomicron and VLDL molecules?

59. Cushing syndrome causes?  

60. In what form is glucose stored in muscle and liver?

61. Excessive galactose in blood and excretion in urine is called

62. Decreased level of haptoglobin is indicative of?

63. Which lipoprotein is the largest and have lowest density? 

64. Which lipoprotein is known as "bad cholesterol"?

65. Which disorder is associated with Vitamin B12 deficiency?

66. Which analyte should be placed on ice immediately after draw?

67. Which hormone inhibits the release of glucose from the liver?

68. What is the process by which glycogen is broken down to glucose? 

69. Which hormone increases blood glucose during stress? 

70. What is the major constituents of cell membranes and outer shells of  lipoprotein molecules? 

71. Which of the following protein is found in urine of a patient with multiple myeloma?

72. Which type of specimen is used for Creatinine clearance test?

73. Which protein binds to free hemoglobin?

74. In what condition would decreased level of alpha-1-antitrypsin be expected?

75. Which hormone inhibits the release of glucose from the liver?

76. What is the major fat in adipose tissues? 

77. Which of the following hormone stimulates lipolysis and  gluconeogenesis?

78. Which of the following hormone is catecholamine?

79. Which of the following carbohydrates is a monosaccharide? 

80. Which of the following condition causes respiratory alkalosis?

81. Which enzyme is decreased in insecticide poisonings? 

82. What type of diabetes is associated with obesity and sedentary lifestyle?

83. Decreased levels of which lipoprotein is associated with increased risk  for coronary artery disease?

84. In what condition would an increased level of serum albumin be expected?

85. Which of the immunoglobulin class is able to cross the placenta from the mother to the fetus? 

86. What is the process of formation of glycogen from glucose called? 

87. Which hormone inhibits the secretion of Growth Hormone?

88. What molecule is formed from one molecule of glycerol and three fatty  acid molecules?

89. Which tumor marker is used for the detection of pancreatic cancer?

90. Which enzyme is elevated in Mumps? 

91. Which substance is released when serum calcium level increases?

92. Which disorder is characterized by buildup of unconjugated bilirubin in the blood due to deficiency of UDPglycuronyltransferase?

93. Which type of lipid consists of one glycerol molecule and two fatty acid  molecules attached via ester bonds?

94. In metabolic alkalosis, bicarbonate is

95. Which ions is the major cation of extracellular fluid?

96. Which of the following disorder is associated with an elevated blood ammonia level? 

97. Where is insulin produced? 

98. What does normal ctCO2, increased pH with decreased PCO2 indicate? 

99. Which marker is used for the detection of colorectal cancer?

100. What is the three-dimensional shape of a protein called?

101. Triglycerides are transported through the body by 

102. What is the major constituents of cell membranes and outer shells of  lipoprotein molecules?

103. Which lipoprotein is the primary carrier of cholesterol?

104. What are positively charged ions called?

105. Osteoporosis is caused by a deficiency in which of the following?

106. Which hormones are secreted by the anterior Pituitary Gland?

107. What color does biuret turn when protein is present?

108. What is the building block of proteins?

109. Which of the following electrolyte is an important buffer system of blood?

110. What is the presence of glucose in urine called? 

111. What is another name for Vitamin B2?

112. The serum concentration of electrolytes is quantified using

113. What does decreased pH and ctCO2 with normal PCO2 indicate? 

114. Which of the following compound is used to assess the glomerular filtration rate (GFR). 

115. Which hormone inhibits release of prolactin?

116. What does increased ctCO2 and pH with normal PCO2 indicate? 

117. What is the process of formation of glycogen from glucose called?

118. What compound is the major nitrogen-containing compound in the blood?

119. What is the process of breaking down glucose to form pyruvate  molecules?

120. The biuret method for the determination of protein concentrations measures the amount of?

121. Which one of the following biochemical marker is used for assessing  heart failure? 

122. Which of the following ion is an anion 

123. Which lipoprotein gives serum a turbid appearance? 

124. Scurvy is caused by a deficiency in which of the following?

125. Which hormones stimulates uterine contractions during childbirth?

126. The structure formed by the sequence of amino acids within a polypeptide chain is?

127. Which of the following glycoprotein is elevated in trophoblastic tumors?

128. What is the major protein found in High-density lipoprotein (HDL)? 

129. What does hydrolysis of lactose yield? 

130. Which enzyme is elevated in prostate cancer? 

131. Which of the following oncofetal antigen is associated with Down syndrome?

132. An onset of diabetes mellitus during pregnancy is known as  

133. Which of the following condition is associated with (XXY)?

134. Which test is used to detect pregnancy?

135. Which hormone inhibits the secretion of thyroid-stimulating hormone?

136. What is a fasting blood glucose level >100 mg/dL called? 

137. Which hormone stimulates spermatogenesis?

138. What is the product of deamination of amino acids in the liver?

139. Which enzyme is elevated in Paget disease?

140. Which blood protein is most responsible for osmotic pressure?

141. Cushing syndrome causes?  

142. High-sensitivity CRP (hs-CRP) of 3.0 mg/L is indicative of  

143. What is the renal threshold for glucose? 

144. Elevated alpha-1-fetoprotein during pregnancy is expected in which of the following condition(s)?

145. Which of the following vitamin is water-soluble?

146. Which of the following immunoglobin is increased in allergies, asthma, and parasitic infections?

147. Which one of the following is the most specific biochemical marker of  myocardial infarction? 

148. A colored stool is seen in

149. What is another name for Vitamin C?

150. Which element distinguishes proteins from carbohydrate and lipid compounds?

151. Which of the following vitamin is fat-soluble?

152. Which of the following vitamin is water-soluble?

153. Which lipoprotein is known as "bad cholesterol"?

154. Which enzyme is elevated in acute pancreatitis? 

155. Which of the following glycoprotein are markers for ovarian and endometrial cancer?

156. What does hydrolysis of lactose yield?  

157. What is the major protein found in Low-density lipoprotein (LDL)? 

158. What is another name for Vitamin B6?

159. Which hormone increases blood glucose by stimulating glycogenolysis?

160. What is normal osmolal gap?

161. Where is insulin produced?

162. Which enzyme deficiency will result in increased sensitivity to  certain muscle relaxant drugs used during surgery? 

163. Which of the following vitamin is water-soluble?

164. Which of the following disorder is associated with an elevated serum uric level? 

165. Which hormone increases blood glucose by stimulating glycogenolysis? 

166. What is another name for Vitamin B12?

167. Which lipoprotein is the largest and have lowest density?

168. What is end product of glucose metabolism in anaerobic condition?

169. Hemorrhagic disease is associated with deficiency of which of the following vitamin?

170. Which protein activates lecithincholesterol acyltransferase  (LCAT) and removes free cholesterol from extrahepatic tissues? 

171. Which disorder is associated with Niacin deficiency? 

172. What is the major waste product of purine catabolism? 

173. Which of the following protein is used to predict the risk of premature birth?

174. What hormone increases osmolality?

175. What molecule is formed from one molecule of glycerol and three fatty  acid molecules? 

176. Which hormone controls water homeostasis?

177. What are negatively charged ions called?

178. Which of the following lipid act as a precursor of bile acids, Vitamin D and  steroids?

179. Which hormone increases blood glucose during stress?

180. Calculate LDL cholesterol given a total cholesterol of 220mg/dl,  65mg/dl of HDL and triglyceride 200 mg/dl 

181. Which disorder is associated with Thiamin deficiency?

182. Which of the following is a tissue-specific marker used to detect prostate cancer?

183. What is end product of glucose metabolism in anaerobic condition? 

184. Excessive galactose in blood and excretion in urine is called

185. What is the normal range of sodium?

186. Which hormone inhibits secretion of insulin, glucagon, and growth  hormone?

187. Which enzyme is useful in forensic cases involving rape?

188.  In gout, which of the following compound deposits in joints and other body tissues? 

189. Which ions is the major cation of intracellular fluid?

190. What type of diabetes is associated with obesity and a sedentary lifestyle? 

191. Which disorder is associated with Vitamin B2 deficiency?

192. What form are carbohydrates stored in the liver and skeletal muscles?

193. In metabolic acidosis, total carbon dioxide is

194. Which hormone regulates salt balance?

195. Which lipoprotein function has an antiatherogenic effect?

196. Which of the following lipid act as a precursor of bile acids, Vitamin D and  steroids?

197. Of the following blood glucose levels, which would you expect to result  in glucose in the urine? 

198. Night blindness is caused by a deficiency in which of the following?

199. Which enzyme deficiency is associated with hemolytic anemia after  ingestion of fava beans? 

200. Which hormones secreted by the anterior pituitary raises blood glucose  levels?

201. What hormone helps regulate Phosphorus?

202. Elevated levels of which lipoprotein is associated with increased risk for  atherosclerosis?

203. What form are carbohydrates stored in the liver and skeletal muscles?

204. Given the following information for an average-size adult, calculate creatinine clearance. Urine creatinine—110 mg/dL Plasma creatinine—1.2 mg/dL Urine volume for 24 hours—1420 ml

205. Which exhibit diurnal variation, with highest levels in the morning?

206. Which protein transports iron?

207. Triglycerides are transported through the body by 

208. Given the following information for an average-size adult, calculate creatinine clearance. Urine creatinine—130 mg/dL Plasma creatinine—1.4 mg/dL Urine volume for 24 hours—1620 ml