Blood Bank QBank

Our question bank has 203 multiple choice questions on all the essential blood transfusion topics. If you are planning on taking ASCP, I will recommend using our question bank.  Topics includes ABO genetics, ABO blood group, Rh blood system, Other blood groups, component storage, antibody identification, antibody screening, crossmatch, donor requirements, ABO blood typing and more.

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Bloodbank Finals

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Category: Bloodbank

1. What is the allowable shelf life of blood with CPD anticoagulants?

 

 

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Category: Bloodbank

2. An ABO type and screen on a patient give the following reactions. Assume the antibody screen is positive.

Anti-A Anti- B Anti- D Rh A1 cell B cell
4+ 0 4+ 0 0 3+

Which donor unit should be selected?

Immediate Spin    37oC Antiglobulin Phase
A positive 0 Not tested Not tested
A negative 0 0 0; Check cell 2+
AB negative 0 0 0; Check cell 0
B negative 2+ 2+ 2+

 

 

Anti P is cold reactive antibody; while others are warm reactive antibodies.

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Category: Bloodbank

3. Which antibody does not fit with the others with respect to optimum phase of reactivity?

Plasma hemoglobin, ammonia, and K+ levels increases

Plasma Na+,  pH and 2,3-BPG levels decreases.

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Category: Bloodbank

4. Which blood group system is associated with McLeod phenotype?

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Category: Bloodbank

5. Iberus Amara has specificity for which antigen?

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Category: Bloodbank

6. An ABO type on a patient gives the following reactions. What is the patient’s blood type?

Anti-A Anti- B Anti- D Rh  A1 cell B cell
0 4+ 4+ 0 3+ 0

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Category: Bloodbank

7. What are the required storage temperature and shelf life of frozen red blood cells?

 

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Category: Bloodbank

8. What antigens are present in a person with blood type O?

 

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Category: Bloodbank

9. An ABO type on a patient gives the following reactions. What is the patient’s blood type?

Anti-A Anti- B Anti- D Rh  A1 cell B cell
4+ 3+ 0 0 0 0

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Category: Bloodbank

10.  Which D phenotype is suspected when a seemingly D-positive person makes anti-D after transfusion with D-positive blood?

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Category: Bloodbank

11. Which antigen is the most immunogenic of Rh antigens?

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Category: Bloodbank

12. An ABO type on a patient gives the following reactions. What is the patient’s blood type?

Anti-A Anti- B Anti- D Rh  A1 cell B cell
0 4+ 0 0 4+ 0

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Category: Bloodbank

13. Which of the following potentiator removes water from the test system and concentrates antibody?

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Category: Bloodbank

14. What is the temperature range for maintaining red blood cells and whole blood during shipping?

 

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Category: Bloodbank

15. What are the storage temperature and shelf life of platelets?

 

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Category: Bloodbank

16. What antigens are present in a person with type A- blood?

 

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Category: Bloodbank

17. What are the required storage temperature and shelf life of whole blood?

 

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Category: Bloodbank

18. Which donor red blood cell unit should be selected first?

Anti-A Anti- B Anti- D Rh control A1 cell B cell
0 4+ 0 0 4+ 0

 

 

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Category: Bloodbank

19. Which antibody serologically mimics Anti-C and Anti D?

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Category: Bloodbank

20. What preservative is used in ATP synthesis to maintain red blood cells stability?

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Category: Bloodbank

21. An ABO type on a patient gives the following reactions. What is the patient’s blood type?

Anti-A Anti- B Anti- D Rh  A1 cell B cell
0 0 4+ 0 4+ 4+

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Category: Bloodbank

22. Agglutinated cells disperse throughout the gel media and concentrate towards the bottom of the microtube. Grade the reaction.

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Category: Bloodbank

23. For the following patient, indicate the component of choice for transfusion therapy. Patient with liver disease

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Category: Bloodbank

24. A patient’s red blood cells gave the following reactions upon phenotyping. Which of the following is the most probable Rh genotype?

D C E c e
0 + 0 0 +

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Category: Bloodbank

25. Which of the following potentiator cause agglutination by reducing the zeta potential between RBCs?

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Category: Bloodbank

26. Which Plasma donor unit can the patient receive?

Anti-A Anti- B Anti- D Rh control A1 cell B cell
4+ 4+ 0 0 0 0

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Category: Bloodbank

27. What antigens are present in a person with type AB- blood?

 

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Category: Bloodbank

28.

When does a pretransfusion specimen expire?

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Category: Bloodbank

29.  How many platelets should platelet concentrates prepared by apheresis contain?

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Category: Bloodbank

30. An anticoagulant that chelates calcium to prevent clotting is called?

MMM

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Category: Bloodbank

31. Blood proteins produced by the immune system in response to a foreign substance in the body are called?

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Category: Bloodbank

32. What blood type can Bombay phenotype individual receive?

 

Kidd, Duffy, MNS blood groups are known for showing dosage

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Category: Bloodbank

33. Which of the following blood group antigens are known for showing dosage?

 

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Category: Bloodbank

34. How long must a donor wait after plasma donation?

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Category: Bloodbank

35. Which Plasma donor unit can the patient receive?

Anti-A Anti- B Anti- D Rh control A1 cell B cell
0 4+ 0 0 3+ 0

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Category: Bloodbank

36. What is the allowable shelf life of blood with Adsol (AS-1, AS-3, orAS-5) anticoagulants?

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Category: Bloodbank

37. What are the required storage temperature and shelf life of Cryoprecipitate?

 

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Category: Bloodbank

38. What blood type is the universal recipient?

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Category: Bloodbank

39. Medium clumps with a slightly cloudy background. Grade the reaction.

 

 

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Category: Bloodbank

40. Which antibody can be neutralized with human breast milk?

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Category: Bloodbank

41. ABO antibodies are

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Category: Bloodbank

42. Use table below to answer this question. What type of antibody will blood type O make?

Blood group Antigen(s) on RBCs Antibodies present in the serum
O

 

None

 

 

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Category: Bloodbank

43. What type of crossmatch should be performed? Below is the result of an antibody screen.

Screening cell 1 Screening cell 2 Screening cell 3
0 0 0

 

 

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Category: Bloodbank

44. Which blood group antigen is located near the RBC membrane and present when S or s is inherited?

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Category: Bloodbank

45. Which cells agglutinate most strongly with Dolichos biflorus lectin?

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Category: Bloodbank

46. What is deferral period for aspirin?

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Category: Bloodbank

47. What are the storage temperature and shelf life of RBCs (irradiated)?

 

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Category: History

48. A term used to describe the Middle colonies because of their fertile soil, ideal for farming is known as?  

MN, Kidd, Duffy are well developed at birth

 

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Category: Bloodbank

49. Which blood group antigen is well developed at birth?

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Category: Bloodbank

50. Large clumps with clear background. Grade the reaction.

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Category: Bloodbank

51. Which of the following carries a 12-month deferral?

 

 

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Category: Bloodbank

52. Which antibody can be neutralized with pooled plasma to allow detection of other antibodies?

 

 

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Category: Bloodbank

53. What type of crossmatch should be performed? Below is the result of an antibody screen

Screening cell 1 Screening cell 2 Screening cell 3
0 0 2+

 

 

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Category: Bloodbank

54. Antigen that shows dosage must be rule out with?

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Category: Bloodbank

55. Predict the blood group using the information below.

Mom’s phenotype is group A, genotype AO

Dad’s phenotype is group B, genotype BB

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Category: Bloodbank

56. What genes are necessary for the production of Leb Antigens?

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Category: Bloodbank

57. Which Plasma donor unit can the patient receive?

Anti-A Anti- B Anti- D Rh control A1 cell B cell
0 0 0 0 3+ 3+

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Category: Bloodbank

58. How often can you donate platelets?

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Category: Bloodbank

59. Which blood group system is associated with resistance to P. vivax malaria?

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Category: Bloodbank

60. What is the component of choice for transfusion for a patient with a hematocrit of 20%. 

 

 

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Category: Bloodbank

61. Which antibody is neutralized by urine to allow detection of other alloantibodies?

 

 

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Category: Bloodbank

62. Which antibody is neutralized in vitro by Lewis substance?

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Category: Bloodbank

63. Predict the blood group using the information below.

Mom’s phenotype is group A, genotype AO​

Dad’s phenotype is group B, genotype BO

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Category: Bloodbank

64. The two phases of humoral response are?

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Category: Bloodbank

65. Individuals with blood group O have

 

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Category: Bloodbank

66. What is a massive transfusion?

 

 

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Category: Bloodbank

67. An ABO type and screen on a patient give the following reactions. Assume the antibody screen is negative.

 

Anti-A Anti- B Anti- D Rh  A1 cell B cell
4+ 4+ 0 0 0 0

 

Which unit should be used to perform crossmatch?

Immediate spin
AB Negative 0
A negative 3+
B negative 1+

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Category: Bloodbank

68. What is being tested in reverse typing?

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Category: Bloodbank

69. What are the required storage temperature and shelf life of fresh frozen plasma (FFP)?

 

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Category: Bloodbank

70. What units are given in massive transfusion?

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Category: Bloodbank

71. Unlike ABO antibodies, anti- D antibody is produced through exposure to D antigen through transfusion or pregnancy and can cause significant hemolytic disease of fetus and newborn (HDFN) or hemolytic transfusion reaction.

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Category: Bloodbank

72.  What blood type is the universal donor?

 

 

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Category: Bloodbank

73. Which blood group system does Anti-Jsa and Anti-Js b belong to?

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Category: Bloodbank

74. What are the storage temperature and shelf life of RBCs (deglycerolized)?

 

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Category: Bloodbank

75. Which cells Agglutinate most strongly with Ulex europaeus lectin?

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Category: Bloodbank

76. What are the storage temperature and shelf life of pooled cryoprecipitate?

 

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Category: Bloodbank

77. Which gene controls the expression of D expression?

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Category: Bloodbank

78. How long must a donor wait after whole blood donation?

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Category: Bloodbank

79. Platelet concentrates prepared by apheresis should contain how many platelets?

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Category: Bloodbank

80. An ABO type on a patient gives the following reactions. What is the patient’s blood type?

Anti-A Anti- B Anti- D Rh  A1 cell B cell
0 0 0 0 4+ 4+
Physical exam Requirements Physical exam Requirements
Minimum Age 17 years

Under 17 years needs parental

consent

Blood pressure 180/100mmHg
Weight 110 Ibs Pulse 50-100bpm
Hematocrit 38% Temperature 99.5 OF (37.5OC)
Hemoglobin (Women) 12.5g/dL Hemoglobin (Men) 13.0g/dL

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Category: Bloodbank

81. A man wants to donate blood. His physical examination reveals the following: weight—120 Ib, pulse—112 bpm, blood pressure—132/74 mm Hg, hematocrit—39%. Which of the following exclusions applies to the prospective donor?

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Category: Bloodbank

82. Use table below to answer this question. What type of antibody will blood type A make?

Blood group Antigen(s) on RBCS Antibodies present in the serum
A

 

A

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Category: Bloodbank

83.

Which antibody is most commonly associated with delayed hemolytic transfusion reactions?

 

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Category: Bloodbank

84. Vicia graminea has specificity for which antigen?

 

 

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Category: Bloodbank

85. Which antigen has a receptor for Haemophilus influenza?

Rh, Kidd, Lewis, P and I blood group are enhanced by enzymes

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Category: Bloodbank

86. Which antigen(s) is enhanced by enzymes?

 

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Category: Bloodbank

87. What is the component of choice for transfusion for a patient with a platelet count of <10.000u/L?

Plasma hemoglobin, ammonia, and K+ levels increases

Plasma Na+,  pH and 2,3-BPG levels decreases.

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Category: Bloodbank

88. Biochemical changes occur during the shelf life of stored blood. Which of the following is a result of this “storage lesion”?

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Category: Bloodbank

89. What is the shelf life of blood component with CPDA-1 anticoagulant?

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Category: Bloodbank

90. What are the two ways ABO typing can be performed?

Physical exam Requirements Physical exam Requirements
Minimum Age 17 years

Under 17 years needs parental

consent

Blood pressure 180/100mmHg
Weight 110 Ibs Pulse 50-100bpm
Hematocrit 38% Temperature 99.5 OF (37.5OC)
Hemoglobin (Women) 12.5g/dL Hemoglobin (Men) 13.0g/dL

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Category: Bloodbank

91. A woman wants to donate blood. Her physical examination reveals the following: temperature—390C, pulse—53 bpm, blood pressure—125/75 mm Hg, hematocrit—38%. Which of the following exclusions apply to the prospective donor?

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Category: Bloodbank

92. Which gene controls the expression of C, c, E, e expression?

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Category: Bloodbank

93. Which autoantibody specificity is found in patients with paroxysmal cold hemoglobinuria?

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Category: Bloodbank

94. What is the component of choice for transfusion for a patient with a hemoglobin of 6g/dl?

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Category: Bloodbank

95. What is being tested in forward typing?

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Category: Bloodbank

96. Which of the following viruses resides exclusively in leukocytes?

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Category: Bloodbank

97. The extract from seeds of Ulex Europeaus has specificity for?

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Category: Bloodbank

98. Identify the antibody.

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Category: Bloodbank

99. Which condition is X- linked and is associated with abnormal RBC morphology, compensated hemolytic anemia, neurological and muscular abnormalities ?

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Category: Bloodbank

100. A patient’s red blood cells gave the following reactions upon phenotyping. Which of the following is the most probable Rh genotype?

 

D C E c e
0 0 + + 0

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Category: Bloodbank

101. The only blood group system in which an individual have antibodies to antigens they lack, without any prior exposure of red blood cells through transfusion or pregnancy is

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Category: Bloodbank

102. What is the storage temperature and shelf life of Granulocyte pheresis?

 

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Category: Bloodbank

103. When do you administer Rhogan to Rh negative mom after giving birth to Rh positive baby ?

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Category: Bloodbank

104. Rh antibodies are primarily of which immunoglobulin class?

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Category: Bloodbank

105. Which Plasma donor unit can the patient receive?

Anti-A Anti- B Anti- D Rh control A1 cell B cell
4+ 0 4+ 0 0 3+

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Category: Bloodbank

106. What type of immunoglobulin is anti-A and anti-B?

The genes GYPA codes for glycophorin A for blood group M and N

The genes GYPB codes for glycophorin B for blood group S and s

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Category: Bloodbank

107. Which blood group system is produced by glycophorin B?

 

 

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Category: Bloodbank

108. Which blood group system do K and k antigens belong to?

 

 

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Category: Bloodbank

109. What is biphasic hemolysin?

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Category: Bloodbank

110. A patient’s red blood cells gave the following reactions upon phenotyping. Which of the following is the most probable Rh genotype?

D C E c e
+ 0 0 + +

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Category: Bloodbank

111. Which immunohematology test is performed to determine in vitro sensitization of RBC’s?

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Category: Bloodbank

112. Which is the class of immunoglobulin uniquely associated with hemolytic disease of the fetus and newborn (HDFN)?

 

 

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Category: Bloodbank

113. The antibody to this high prevalence antigen appears shiny and refractile under the microscope.

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Category: Bloodbank

114. What is the component of choice for transfusion for a patient with Sickle cell anemia?

While D antigen is the most immunogenic, c antigen is the next Rh antigen to elicit immune response followed by E, C, and e

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Category: Bloodbank

115. Which Rh antigen is the most immunogenic?

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Category: Bloodbank

116. Individuals with hh genotype, anti-A, anti-B anti-A, B, and Anti-H are

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Category: Bloodbank

117. How many drop(s) of a patient serum is added in reverse blood typing?

 

 

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Category: Bloodbank

118. What is the component of choice for transfusion for a patient with liver disease?

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Category: Bloodbank

119. Leukoreduced RBCs must contain less than______?   Leukocytes and retain at least_____?

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Category: Bloodbank

120. Which donor RBC unit should be selected first?

Anti-A Anti- B Anti- D Rh control A1 cell B cell
4+ 0 4+ 0 0 4+

 

 

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Category: Bloodbank

121. Kernicterus is caused by effect of?

Physical exam Requirements Physical exam Requirements
Minimum Age 17 years

Under 17 years needs parental

consent

Blood pressure 180/100mmHg
Weight 110 Ibs Pulse 50-100bpm
Hematocrit 38% Temperature 99.5 OF (37.5OC)
Hemoglobin (Women) 12.5g/dL Hemoglobin (Men) 13.0g/dL

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Category: Bloodbank

122. Which of the following would be cause for deferral for a male donor?

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Category: Bloodbank

123.  Agglutination cells form a cell layer at the top of the gel media. Grade the reaction.

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Category: Bloodbank

124. What are the storage temperature and shelf life of pooled platelets?

 

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Category: Bloodbank

125. What are the required storage temperature and shelf life of thawed fresh frozen plasma (FFP)?

 

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Category: Bloodbank

126. What antigens are present in a person with type B- blood?

 

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Category: Bloodbank

127. What is the allowable shelf life of blood with CP2D anticoagulants?

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Category: Bloodbank

128. Which of the following would be a cause permanent deferral?

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Category: Bloodbank

129. Transfusing one unit of RBC increases patient’s hematocrit by

Anti Jka is warm antibody; while others are cold reactive antibodies.

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Category: Bloodbank

130. Which antibody does not fit with the others with respect to optimum phase of reactivity?

 

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Category: Bloodbank

131. A patient’s red blood cells gave the following reactions upon phenotyping. Which of the following is the most probable Rh genotype? 

D C E c e
+ + + 0 0

 

 

 

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Category: Bloodbank

132. What is the result of the ABO, Rh, and antibody screen test?

Anti-A Anti- B Anti- D Rh  A1 cell B cell
4+ 4+ 4+ 0 0 0
 
Screening cell 1
Screening cell 2
Screening cell 3
0 0 2+

 

 

 

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Category: Bloodbank

133. What is the result of the ABO, Rh, and antibody screen test?

Anti-A Anti- B Anti- D Rh  A1 cell B cell
4+ 0 0 0 0 4+
 
Screening cell 1
Screening cell 2
Screening cell 3
0 0 0

 

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Category: Bloodbank

134. Which blood group system is associated with Chronic Granulomatous Disease (CGD)?

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Category: Bloodbank

135. Which blood type is recommended by AABB Standards to be given to all weak-D recipients?

Plasma hemoglobin, ammonia, and K+ levels increases

Plasma Na+,  pH and 2,3-BPG levels decreases.

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Category: Bloodbank

136. Biochemical changes occur during the shelf life of stored blood. Which of the following is a result of this “storage lesion”?

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Category: Bloodbank

137. Rh antibodies react best at what temperature?

 

 

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Category: Bloodbank

138. Which blood group system does Anti-Jka and Anti-Jkb belong to?

Physical exam Requirements Physical exam Requirements
Minimum Age 17 years

Under 17 years needs parental

consent

Blood pressure 180/100mmHg
Weight 110 Ibs Pulse 50-100bpm
Hematocrit 38% Temperature 99.5 OF (37.5OC)
Hemoglobin (Women) 12.5g/dL Hemoglobin (Men) 13.0g/dL

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Category: Bloodbank

139. Which of the following would be cause for deferral for a female donor?

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Category: Bloodbank

140. Rh antibodies is associated with which clinical condition?

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Category: Bloodbank

141. What type of immunoglobulin is anti-A,B?

Anti-P1  is easily inhibited with P1 substance(Hydatid cyst fluid)

 

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Category: Bloodbank

142. Which antibody is neutralized by hydatid cyst fluid to allow detection of other antibodies?

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Category: Bloodbank

143. Use table below to answer this question. What type of antibody will blood type AB make?

Blood group Antigen(s) on RBCS Antibodies present in the serum
AB

 

A and B

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Category: Physics

144. A term used to describe the study of motion is called?

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Category: Bloodbank

145. The causative agent of Chagas disease is

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Category: Bloodbank

146. Which antigen is expressed when c and e are present on the same haplotype?

 

 

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Category: Bloodbank

147. Which blood group system do Anti-Fya and Anti-Fybelong to?

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Category: Bloodbank

148. All cells pass through the gel media forming a cell button at the bottom of the microtube. Grade this gel reaction.

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Category: Bloodbank

149. Which of the following RBC abnormality is associated with Rh null syndrome?

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Category: Bloodbank

150. An ABO type on a patient gives the following reactions. What is the patient’s blood type?

Anti-A Anti- B Anti- D Rh  A1 cell B cell
4+ 0 4+ 0 0 3+

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Category: Bloodbank

151. The Rh systems genes are?

Plasma hemoglobin, ammonia, and K+ levels increases

Plasma Na+,  pH and 2,3-BPG levels decreases.

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Category: Bloodbank

152. Biochemical changes occur during the shelf life of stored blood. Which of the following is a result of this “storage lesion”?

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Category: Coagulation

153. A hereditary thrombocytes disorder that is caused by lack of functional GPIb-IX-V complexes on the platelet surface, and is associated with presence of large platelets, increased MPV, decreased aggregation response to ristocetin, and normal vWF: RCo, vWF: Ag?

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Category: Bloodbank

154. What is the component of choice for transfusion for a patient with neutropenia (<500 WBC/mm3)?

 

The genes GYPA codes for glycophorin A for blood group M and N

The genes GYPB codes for glycophorin B for blood group S and s

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Category: Bloodbank

155. Which blood group system is produced by glycophorin A?

 

 

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Category: Bloodbank

156. Which of the following are antibodies to low-frequency antigens?

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Category: Bloodbank

157. A patient’s red blood cells gave the following reactions upon phenotyping. Which of the following is the most probable Rh genotype?

D C E c e

 

+ + + 0 0

 

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Category: Bloodbank

158. Solid button with clear background. Grade the reaction.

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Category: Uncategorized

159. Transfusing one unit of RBC increases patient’s hemoglobin approximately by

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Category: Bloodbank

160. Which donor RBC unit should be selected?

Anti-A Anti- B Anti- D Rh control A1 cell B cell
4+ 4+ 0 0 0 0

 

 

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Category: Bloodbank

161.

Which of the following potentiator cause agglutination by lowering zeta potential and increasing the rate of antibody uptake?

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Category: Bloodbank

162. Predict the blood group using the information below.

Mom’s phenotype is group O, genotype OO

Dad’s phenotype is group O, genotype OO

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Category: Bloodbank

163. Which Rh phenotype is written as D- –  or  -D- ?

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Category: Bloodbank

164. Which autoantibody is associated with early abortion?

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Category: Bloodbank

165. What are the four main blood groups in the ABO blood group system?

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Category: Bloodbank

166. Rh antigens are proteins, unlike ABO antigens which are glycolipids.

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Category: Bloodbank

167. What is the component of choice for transfusion for a patient with Fibrinogen deficiency?

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Category: Bloodbank

168. Which donor RBC unit should be selected?

Anti-A Anti- B Anti- D Rh control A1 cell B cell
0 0 4+ 0 3+ 3+
 

 

 

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Category: Bloodbank

169. Predict the blood group using the information below.

Mom’s phenotype is group B, genotype BO

Dad’s phenotype is group O, genotype OO

 

 

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Category: Bloodbank

170. What is the patient’s ABO, Rh, and antibody screen?

Anti-A Anti- B Anti- D Rh  A1 cell B cell
0 0 0 0 4+ 3+
 
Screening cell 1
Screening cell 2
Screening cell 3
0 0 0

 

 

 

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Category: Bloodbank

171. Which of the following antibody is an IgG biphasic antibody in Donath-Landsteiner antibody test?

 

 

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Category: Bloodbank

172. What is the patient’s ABO, Rh, and antibody screen?

Anti-A Anti- B Anti- D Rh  A1 cell B cell
0 0 4+ 0 4+ 3+
 
Screening cell 1
Screening cell 2
Screening cell 3
0 0 2+

 

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Category: Bloodbank

173. Many small clumps with a cloudy background. Grade the reaction 

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Category: Bloodbank

174. For the following patient, indicate the component of choice for transfusion.

IgA deficient patient with anti-IgA antibodies

Plasma hemoglobin, ammonia, and K+ levels increases

Plasma Na+,  pH and 2,3-BPG levels decreases.

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Category: Bloodbank

175. Which autoantibody is associated with Echinococcus granulosis?