Blood Bank QBank -

Our question bank has 203 multiple choice questions on all the essential blood transfusion topics. If you are planning on taking ASCP, I will recommend using our question bank. Topics includes ABO genetics, ABO blood group, Rh blood system, Other blood groups, component storage, antibody identification, antibody screening, crossmatch, donor requirements, ABO blood typing and more.

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Bloodbank Finals

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Category: Bloodbank

1. What is the allowable shelf life of blood with CPD anticoagulants?

A. 21 days

B. 35 days

C. 42 days

D. 24 days

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Category: Bloodbank

2. An ABO type and screen on a patient give the following reactions. Assume the antibody screen is positive.

Anti-A	Anti- B	Anti- D	Rh	A1 cell	B cell
4+	0	4+	0	0	3+

Which donor unit should be selected?

	Immediate Spin	37^oC	Antiglobulin Phase
A positive	0	Not tested	Not tested
A negative	0	0	0; Check cell 2+
AB negative	0	0	0; Check cell 0
B negative	2+	2+	2+

A. A positive

B. A negative

C. AB negative

D. B negative

Anti P is cold reactive antibody; while others are warm reactive antibodies.

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Category: Bloodbank

3. Which antibody does not fit with the others with respect to optimum phase of reactivity?

A. Anti Jka

B. Anti-Fya

C. Anti-S

D. Anti-P

Plasma hemoglobin, ammonia, and K+ levels increases

Plasma Na+, pH and 2,3-BPG levels decreases.

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Category: Bloodbank

4. Which blood group system is associated with McLeod phenotype?

A. Kidd

B. Kell

C. Duffy

D. Lutheran

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Category: Bloodbank

5. Iberus Amara has specificity for which antigen?

A. A1 antigen

B. H antigen

C. M antigen

D. N antigen

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Category: Bloodbank

6. An ABO type on a patient gives the following reactions. What is the patient’s blood type?

Anti-A	Anti- B	Anti- D	Rh	A1 cell	B cell
0	4+	4+	0	3+	0

A. A positive

B. B positive

C. B negative

D. O negative

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Category: Bloodbank

7. What are the required storage temperature and shelf life of frozen red blood cells?

A. Storage-18°C, expires in 7 years

B. Storage -65°C, expires in 1 year

C. Storage -65°C, expires in 10 years

D. Storage -18°C, expires in 10 years

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Category: Bloodbank

8. What antigens are present in a person with blood type O?

A. A antigen

B. None

C. B antigens

D. A and B antigens

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Category: Bloodbank

9. An ABO type on a patient gives the following reactions. What is the patient’s blood type?

Anti-A	Anti- B	Anti- D	Rh	A1 cell	B cell
4+	3+	0	0	0	0

A. A positive

B. A negative

C. AB negative

D. O negative

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Category: Bloodbank

10. Which D phenotype is suspected when a seemingly D-positive person makes anti-D after transfusion with D-positive blood?

A. Partial D

B. Weak D

C. Rh null

D. D deletion

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Category: Bloodbank

11. Which antigen is the most immunogenic of Rh antigens?

A. E

B. e

C. D

D. c

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Category: Bloodbank

12. An ABO type on a patient gives the following reactions. What is the patient’s blood type?

Anti-A	Anti- B	Anti- D	Rh	A1 cell	B cell
0	4+	0	0	4+	0

A. A positive

B. B positive

C. AB negative

D. B negative

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Category: Bloodbank

13. Which of the following potentiator removes water from the test system and concentrates antibody?

A. Polyethylene glycol

B. Low Ionic Strength Solution

C. Proteolytic Enzymes

D. Bovine Serum Albumin (BSA)

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Category: Bloodbank

14. What is the temperature range for maintaining red blood cells and whole blood during shipping?

A. 20-24°C

B. 1-10°C

C. 1-12°C

D. 1-18°C

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Category: Bloodbank

15. What are the storage temperature and shelf life of platelets?

A. Storage 20-24°C with rotation, expires in 5 days

B. Storage 20-24°C with rotation, expires in 2 days

C. Storage 20-28°C with rotation, expires in 5 days

D. Storage 20-24°C with rotation, expires in 24 hours

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Category: Bloodbank

16. What antigens are present in a person with type A- blood?

A. A antigens

B. B antigens

C. AB antigens

D. None

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Category: Bloodbank

17. What are the required storage temperature and shelf life of whole blood?

A. Storage 1-6°C with CPDA-1, 32 days

B. Storage 1-6°C with CPDA-1, 35 days

C. Storage 1-6°C with CPDA-1, 45 days

D. Storage 1-6°C with CPDA-1, 21 days

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Category: Bloodbank

18. Which donor red blood cell unit should be selected first?

Anti-A	Anti- B	Anti- D	Rh control	A1 cell	B cell
0	4+	0	0	4+	0

A. B positive

B. A positive

C. B negative

D. A negative

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Category: Bloodbank

19. Which antibody serologically mimics Anti-C and Anti D?

A. Anti-C

B. Anti-E

C. Anti-D

D. Anti- G

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Category: Bloodbank

20. What preservative is used in ATP synthesis to maintain red blood cells stability?

A. Citrate

B. Sodium biphosphate

C. Dextrose

D. Adenine

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Category: Bloodbank

21. An ABO type on a patient gives the following reactions. What is the patient’s blood type?

Anti-A	Anti- B	Anti- D	Rh	A1 cell	B cell
0	0	4+	0	4+	4+

A. O positive

B. A positive

C. AB positive

D. B negative

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Category: Bloodbank

22. Agglutinated cells disperse throughout the gel media and concentrate towards the bottom of the microtube. Grade the reaction.

A. 3+

B. 2+

C. 1+

D. 4+

E. Negative

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Category: Bloodbank

23. For the following patient, indicate the component of choice for transfusion therapy. Patient with liver disease

A. Irradiated RBCs

B. Fresh frozen plasma

C. Platelets frozen plasma

D. Granulocyte concentrates

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Category: Bloodbank

24. A patient’s red blood cells gave the following reactions upon phenotyping. Which of the following is the most probable Rh genotype?

D	C	E	c	e
0	+	0	0	+

A. DCe; D, C, e

B. dCe; d, C, e

C. Dce; D, C, E

D. DCE; D, C, E

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Category: Bloodbank

25. Which of the following potentiator cause agglutination by reducing the zeta potential between RBCs?

A. Polyethylene glycol

B. Low Ionic Strength Solution

C. Proteolytic Enzymes

D. Bovine Serum Albumin (BSA)

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Category: Bloodbank

26. Which Plasma donor unit can the patient receive?

Anti-A	Anti- B	Anti- D	Rh control	A1 cell	B cell
4+	4+	0	0	0	0

A. AB negative

B. B negative

C. B and AB negative

D. O, A, B, AB plasma

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Category: Bloodbank

27. What antigens are present in a person with type AB- blood?

A. A antigen

B. None

C. B antigens

D. A and B antigens

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Category: Bloodbank

28.

When does a pretransfusion specimen expire?

A. 7 days

B. 3 Days

C. 2 days

D. 2 Weeks

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Category: Bloodbank

29. How many platelets should platelet concentrates prepared by apheresis contain?

A. 5×10^11

B. 3×10^10

C. 3×10^11

D. 5×10^10

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Category: Bloodbank

30. An anticoagulant that chelates calcium to prevent clotting is called?

A. Citrate

B. Sodium biphosphate

C. Dextrose

D. Adenine

MMM

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Category: Bloodbank

31. Blood proteins produced by the immune system in response to a foreign substance in the body are called?

A. Antigens

B. Antibodies

C. Immunogens

D. Immune cells

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Category: Bloodbank

32. What blood type can Bombay phenotype individual receive?

A. Type O Negative

B. Blood from only Bombay individuals

C. Type O positive

D. Group AB

Kidd, Duffy, MNS blood groups are known for showing dosage

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Category: Bloodbank

33. Which of the following blood group antigens are known for showing dosage?

A. MNS

B. Duffy

C. Kidd

D. All of the above

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Category: Bloodbank

34. How long must a donor wait after plasma donation?

A. 7 days

B. 28 days

C. 8 Weeks

D. 24 hours

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Category: Bloodbank

35. Which Plasma donor unit can the patient receive?

Anti-A	Anti- B	Anti- D	Rh control	A1 cell	B cell
0	4+	0	0	3+	0

A. AB positive

B. B negative

C. B and AB negative

D. O, A, B, AB plasma

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Category: Bloodbank

36. What is the allowable shelf life of blood with Adsol (AS-1, AS-3, orAS-5) anticoagulants?

A. 42 days

B. 35 days

C. 21 days

D. 24 days

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Category: Bloodbank

37. What are the required storage temperature and shelf life of Cryoprecipitate?

A. Storage-18°C, expires in 7 years

B. Storage -65°C, expires in 1 years

C. Storage -65°C, expires in 14 year s

D. Storage -18°C, expires in 1 year

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Category: Bloodbank

38. What blood type is the universal recipient?

A. Group type A

B. Group type O

C. Group type AB

D. Group type B

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Category: Bloodbank

39. Medium clumps with a slightly cloudy background. Grade the reaction.

A. 4+

B. 3+

C. 2+

D. 1+

E. Negative

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Category: Bloodbank

40. Which antibody can be neutralized with human breast milk?

A. Anti- Yta

B. Anti-Lu

C. Anti-I

D. Lewis

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Category: Bloodbank

41. ABO antibodies are

A. Naturally occurring and react at room temperature

B. Naturally occurring, activates complement, and reacts at 37oC

C. Acquired through blood transfusion and reacts at warmer temperature

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Category: Bloodbank

42. Use table below to answer this question. What type of antibody will blood type O make?

Blood group

Antigen(s) on RBCs

Antibodies present in the serum

None

A. Anti-A

B. Anti-B

C. None

D. Anti-A,B

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Category: Bloodbank

43. What type of crossmatch should be performed? Below is the result of an antibody screen.

Screening cell 1	Screening cell 2	Screening cell 3
0	0	0

A. Immediate Spin

B. Extended Crossmatch

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Category: Bloodbank

44. Which blood group antigen is located near the RBC membrane and present when S or s is inherited?

A. S antigen

B. G antigen

C. U Antigen

D. M antigen

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Category: Bloodbank

45. Which cells agglutinate most strongly with Dolichos biflorus lectin?

A. A1 antigen

B. H antigen

C. M antigen

D. N antigen

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Category: Bloodbank

46. What is deferral period for aspirin?

A. 7 days

B. 5 days

C. 72 hours

D. 2 weeks

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Category: Bloodbank

47. What are the storage temperature and shelf life of RBCs (irradiated)?

A. Storage 1-6°C, expires in 28 days

B. Storage 1-6°C, expires in 28 days on originally assigned outdate

C. Storage 1-6°C, expires in 24 days

D. A and B

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Category: History

48. A term used to describe the Middle colonies because of their fertile soil, ideal for farming is known as?

A. Sufficient colonies

B. Bountiful colonies

C. flourbasket colonies

D. Breadbasket colonies

MN, Kidd, Duffy are well developed at birth

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Category: Bloodbank

49. Which blood group antigen is well developed at birth?

A. P

B. Lu

C. Kidd

D. P1

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Category: Bloodbank

50. Large clumps with clear background. Grade the reaction.

A. 4+

B. 2+

C. 1+

D. Negative

E. 3+

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Category: Bloodbank

51. Which of the following carries a 12-month deferral?

A. Donor lived in UK for more than 3 months between 1980-1996

B. Donor Incarcerated for 10 days

C. Recipient of human growth hormone

D. Donor is HIV positive

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Category: Bloodbank

52. Which antibody can be neutralized with pooled plasma to allow detection of other antibodies?

A. Anti- Yta

B. Anti-Lu

C. Anti-Sda

D. Anti-Ch (Chido)

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Category: Bloodbank

53. What type of crossmatch should be performed? Below is the result of an antibody screen

Screening cell 1	Screening cell 2	Screening cell 3
0	0	2+

A. Immediate Spin

B. Extended Crossmatch

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Category: Bloodbank

54. Antigen that shows dosage must be rule out with?

A. Cold panel

B. Heterozygous

C. Homozygous cell

D. Auto adsorption

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Category: Bloodbank

55. Predict the blood group using the information below.

Mom’s phenotype is group A, genotype AO

Dad’s phenotype is group B, genotype BB

A. 50% Group AB and 50% Group B

B. 25% AB and 75% group B

C. 100% AB

D. 50% Group AB and 50% Group O

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Category: Bloodbank

56. What genes are necessary for the production of Le^bAntigens?

A. Se genes

B. Le and Se genes

C. H genes

D. H and Se genes

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Category: Bloodbank

57. Which Plasma donor unit can the patient receive?

Anti-A	Anti- B	Anti- D	Rh control	A1 cell	B cell
0	0	0	0	3+	3+

A. A positive

B. B positive

C. AB positive

D. O, A, B, AB negative

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Category: Bloodbank

58. How often can you donate platelets?

A. 24 times a year

B. 24 hours

C. 8 Weeks

D. 2 weeks

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Category: Bloodbank

59. Which blood group system is associated with resistance to P. vivax malaria?

A. Anti P

B. Anti- Fya

C. Anti Fya-b-

D. Anti-Jkb

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Category: Bloodbank

60. What is the component of choice for transfusion for a patient with a hematocrit of 20%.

A. RBCs

B. Washed RBCs

C. Cryoprecipitate

D. Platelets

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Category: Bloodbank

61. Which antibody is neutralized by urine to allow detection of other alloantibodies?

A. Anti- Yta

B. Anti-Lu

C. Anti-Sda

D. Anti-V

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Category: Bloodbank

62. Which antibody is neutralized in vitro by Lewis substance?

A. Anti- Yta

B. Anti-Lu

C. Anti-Sda

D. Lewis

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Category: Bloodbank

63. Predict the blood group using the information below.

Mom’s phenotype is group A, genotype AO

Dad’s phenotype is group B, genotype BO

A. 50% Group AB and 50% Group B

B. 25% AB, 25% Group O, 25% Group A and 25% group B

C. 100% AB

D. 50% Group A and 50% Group O

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Category: Bloodbank

64. The two phases of humoral response are?

A. Innate and adaptive

B. Primary and Secondary

C. Primary and Tertiary

D. Immediate and Delayed

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Category: Bloodbank

65. Individuals with blood group O have

A. B antigens on their RBC’s

B. A antigens on their RBC’s

C. Anti-A antibody

D. Anti-A, B antibody

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Category: Bloodbank

66. What is a massive transfusion?

A. Replacement by transfusion of 10 units of red cells in 8 hours, in a response to massive and uncontrolled hemorrhage

B. Replacement by transfusion of 8-10 units of red cells in 12 hours, in response to massive and uncontrolled hemorrhage

C. Replacement by transfusion of 10 units of red cells within 24 hours, in response to massive and uncontrolled hemorrhage

D. Replacement by transfusion of 12 units of red cells in 12 hours, in response to massive and uncontrolled hemorrhage

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Category: Bloodbank

67. An ABO type and screen on a patient give the following reactions. Assume the antibody screen is negative.

Anti-A	Anti- B	Anti- D	Rh	A1 cell	B cell
4+	4+	0	0	0	0

Which unit should be used to perform crossmatch?

	Immediate spin
AB Negative	0
A negative	3+
B negative	1+

A. AB negative

B. A negative

C. B negative

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Category: Bloodbank

68. What is being tested in reverse typing?

A. Patient’s red cells to detect ABO antibodies present

B. Patient’s serum to detect ABO antibodies present

C. Patient’s red cells to detect ABO antigens present

D. Patient’s serum to detect ABO antigens present

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Category: Bloodbank

69. What are the required storage temperature and shelf life of fresh frozen plasma (FFP)?

A. Storage -65°C, expires in 7 years

B. Storage -18°C, expires in 7 years

C. Storage -65°C, expires in 1 year

D. Storage -28°C, expires in 1 year

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Category: Bloodbank

70. What units are given in massive transfusion?

A. 4 packed O negative red blood cells, 2 AB fresh frozen plasma and 1 O negative platelet apheresis

B. 4 packed red blood cells, 2 cryoprecipitate and 1 platelet apheresis

C. 2 packed red blood cells, 2 fresh frozen plasma and 1 platelet apheresis

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Category: Bloodbank

71. Unlike ABO antibodies, anti- D antibody is produced through exposure to D antigen through transfusion or pregnancy and can cause significant hemolytic disease of fetus and newborn (HDFN) or hemolytic transfusion reaction.

A. True

B. False

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Category: Bloodbank

72. What blood type is the universal donor?

A. Group type A

B. Group type O

C. Group type AB

D. Group type B

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Category: Bloodbank

73. Which blood group system does Anti-Js^a and Anti-Js ^bbelong to?

A. Kell

B. Kidd

C. Duffy

D. Lutheran

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Category: Bloodbank

74. What are the storage temperature and shelf life of RBCs (deglycerolized)?

A. Storage 1-6°C, expires in 24 hours after thawing

B. Storage 1-6°C, expires in 8 hours after thawing

C. Storage 1-6°C, expires in 48 hours after thawing

D. Storage 1-10°C, expires in 48 hours after thawing

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Category: Bloodbank

75. Which cells Agglutinate most strongly with Ulex europaeus lectin?

A. H antigen

B. A1 antigen

C. M antigen

D. N antigen

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Category: Bloodbank

76. What are the storage temperature and shelf life of pooled cryoprecipitate?

A. Storage 20-24°C with rotation, expires 12 hours after pooling

B. Storage 20-24°C with rotation, expires 4 hours after pooling

C. Storage 20-28°C with rotation, expires 5 days after pooling

D. Storage 20-24°C, expires 8 hours after pooling

77 / 205

Category: Bloodbank

77. Which gene controls the expression of D expression?

A. RHCE

B. RHCD

C. RHCD

D. RHD

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Category: Bloodbank

78. How long must a donor wait after whole blood donation?

A. 16 Weeks

B. 24 Weeks

C. 56 days

D. 3 months

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Category: Bloodbank

79. Platelet concentrates prepared by apheresis should contain how many platelets?

A. 3 x 10^10

B. 5.5 X 10^10

C. 3 x 10^11

D. 5.5 X 10^6

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Category: Bloodbank

80. An ABO type on a patient gives the following reactions. What is the patient’s blood type?

Anti-A	Anti- B	Anti- D	Rh	A1 cell	B cell
0	0	0	0	4+	4+

A. O positive

B. A positive

C. AB positive

D. O negative

Physical exam	Requirements	Physical exam	Requirements
Minimum Age	17 years Under 17 years needs parental consent	Blood pressure	180/100mmHg
Weight	110 Ibs	Pulse	50-100bpm
Hematocrit	38%	Temperature	99.5 ^OF (37.5^OC)
Hemoglobin (Women)	12.5g/dL	Hemoglobin (Men)	13.0g/dL

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Category: Bloodbank

81. A man wants to donate blood. His physical examination reveals the following: weight—120 Ib, pulse—112 bpm, blood pressure—132/74 mm Hg, hematocrit—39%. Which of the following exclusions applies to the prospective donor?

A. Pulse too high

B. Weight too low

C. Hematocrit too low

D. Blood Pressure too low

82 / 205

Category: Bloodbank

82. Use table below to answer this question. What type of antibody will blood type A make?

Blood group

Antigen(s) on RBCS

Antibodies present in the serum

A. Anti-A

B. Anti-B

C. Anti C

D. Anti-A,B

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Category: Bloodbank

83.

Which antibody is most commonly associated with delayed hemolytic transfusion reactions?

A. Duffy

B. Kidd

C. Kell

D. MNS

84 / 205

Category: Bloodbank

84. Vicia graminea has specificity for which antigen?

A. N antigen

B. M antigen

C. A1 antigen

D. H antigen

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Category: Bloodbank

85. Which antigen has a receptor for Haemophilus influenza?

A. Yta

B. Cra

C. Kna

D. AnWj

Rh, Kidd, Lewis, P and I blood group are enhanced by enzymes

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Category: Bloodbank

86. Which antigen(s) is enhanced by enzymes?

A. Rh

B. Kidd

C. Lewis

D. All of the above

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Category: Bloodbank

87. What is the component of choice for transfusion for a patient with a platelet count of <10.000u/L?

A. Fresh Frozen Plasma

B. Platelets

C. Washed RBCs

D. Granulocyte concentrates

Plasma hemoglobin, ammonia, and K+ levels increases

Plasma Na+, pH and 2,3-BPG levels decreases.

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Category: Bloodbank

88. Biochemical changes occur during the shelf life of stored blood. Which of the following is a result of this “storage lesion”?

A. Increase in pH

B. Increase in plasma K+

C. Increase in plasma Na+

D. Decrease in plasma hemoglobin

89 / 205

Category: Bloodbank

89. What is the shelf life of blood component with CPDA-1 anticoagulant?

A. 42 days

B. 35 days

C. 21 days

D. 24 days

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Category: Bloodbank

90. What are the two ways ABO typing can be performed?

A. Forward and front type

B. Reverse and back typing

C. Forward and Inverse typing

D. Forward and reverse typing

Physical exam	Requirements	Physical exam	Requirements
Minimum Age	17 years Under 17 years needs parental consent	Blood pressure	180/100mmHg
Weight	110 Ibs	Pulse	50-100bpm
Hematocrit	38%	Temperature	99.5 ^OF (37.5^OC)
Hemoglobin (Women)	12.5g/dL	Hemoglobin (Men)	13.0g/dL

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Category: Bloodbank

91. A woman wants to donate blood. Her physical examination reveals the following: temperature—39⁰C, pulse—53 bpm, blood pressure—125/75 mm Hg, hematocrit—38%. Which of the following exclusions apply to the prospective donor?

A. Pulse too high

B. Temperature too high

C. Hematocrit too low

D. Blood Pressure too low

92 / 205

Category: Bloodbank

92. Which gene controls the expression of C, c, E, e expression?

A. RHCD

B. RHD

C. RHCE

D. RHDC

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Category: Bloodbank

93. Which autoantibody specificity is found in patients with paroxysmal cold hemoglobinuria?

A. Auto anti I

B. Anti P

C. Anti i

D. Anti Pk

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Category: Bloodbank

94. What is the component of choice for transfusion for a patient with a hemoglobin of 6g/dl?

A. Washed RBCS

B. Fresh frozen plasma

C. Cryoprecipitate

D. RBCs

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Category: Bloodbank

95. What is being tested in forward typing?

A. Patient’s red cells to detect ABO antibodies present

B. Patient’s serum to detect ABO antibodies present

C. Patient’s red cells to detect ABO antigens present

D. Patient’s serum to detect ABO antigens present

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Category: Bloodbank

96. Which of the following viruses resides exclusively in leukocytes?

A. CMV

B. HIV

C. HCV

D. HAV

97 / 205

Category: Bloodbank

97. The extract from seeds of Ulex Europeaus has specificity for?

A. A1 antigen

B. H antigen

C. N antigen

D. M antigen

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Category: Bloodbank

98. Identify the antibody.

A. Anaphylactic nonhemolytic transfusion reaction

B. Transfusion-associated circulatory overload

C. Febrile nonhemolytic transfusion reaction

D. Transfusion-Associated Graft-versus-Host Disease

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Category: Bloodbank

99. Which condition is X- linked and is associated with abnormal RBC morphology, compensated hemolytic anemia, neurological and muscular abnormalities ?

A. Rh null

B. McLeod phenotype

C. Stomatocytosis

D. Graves Disease

100 / 205

Category: Bloodbank

100. A patient’s red blood cells gave the following reactions upon phenotyping. Which of the following is the most probable Rh genotype?

D	C	E	c	e
0	0	+	+	0

A. dCe; d, C, E

B. dcE; d, c, E

C. DCe; D, C, e

D. DCE; D, C, E

101 / 205

Category: Bloodbank

101. The only blood group system in which an individual have antibodies to antigens they lack, without any prior exposure of red blood cells through transfusion or pregnancy is

A. Rh system

B. Lewis blood system

C. Duffy System

D. ABO blood system

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Category: Bloodbank

102. What is the storage temperature and shelf life of Granulocyte pheresis?

A. Storage 1-6°C, expires in 5 days

B. Storage 20-24°C, expires 4 hours after pooling

C. Storage 20-24°C, expires 4 days

D. Storage 20-24°C, expires in 24 hours

103 / 205

Category: Bloodbank

103. When do you administer Rhogan to Rh negative mom after giving birth to Rh positive baby ?

A. Within 72 hours

B. 7 days

C. 21 days

D. two weeks

104 / 205

Category: Bloodbank

104. Rh antibodies are primarily of which immunoglobulin class?

A. IgM

B. IgG

C. IgE

D. IgA

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Category: Bloodbank

105. Which Plasma donor unit can the patient receive?

Anti-A	Anti- B	Anti- D	Rh control	A1 cell	B cell
4+	0	4+	0	0	3+

A. A and AB positive

B. B negative

C. B and AB negative

D. O, A, B, AB plasma

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Category: Bloodbank

106. What type of immunoglobulin is anti-A and anti-B?

A. IgM

B. IgA

C. IgG

D. IgE

The genes GYPA codes for glycophorin A for blood group M and N

The genes GYPB codes for glycophorin B for blood group S and s

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Category: Bloodbank

107. Which blood group system is produced by glycophorin B?

A. MNS

B. Ss

C. Lewis

D. MN

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Category: Bloodbank

108. Which blood group system do K and k antigens belong to?

A. Kell

B. Lutheran

C. Duffy

D. Kidd

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Category: Bloodbank

109. What is biphasic hemolysin?

A. Binds to RBCs at 37°C and activate complement at 4°C

B. Binds to RBCs at low temperatures and activate complement at 37°C

C. Binds to RBCs at 37°C and activate complement

D. Activate complement at 37°C

110 / 205

Category: Bloodbank

110. A patient’s red blood cells gave the following reactions upon phenotyping. Which of the following is the most probable Rh genotype?

D	C	E	c	e
+	0	0	+	+

A. DCE; D, C, e

B. DcE; D, c, E

C. DCe; D, C, e

D. Dce; D, c, e

111 / 205

Category: Bloodbank

111. Which immunohematology test is performed to determine in vitro sensitization of RBC’s?

A. Indirect Antiglobulin Test (IAT)

B. Direct Antiglobulin Test

C. Weak D

D. Elution

112 / 205

Category: Bloodbank

112. Which is the class of immunoglobulin uniquely associated with hemolytic disease of the fetus and newborn (HDFN)?

A. IgM

B. IgG

C. IgE

D. IgA

113 / 205

Category: Bloodbank

113. The antibody to this high prevalence antigen appears shiny and refractile under the microscope.

A. Anti- Yta

B. Anti-Sda

C. Anti-I

D. Anti-V

114 / 205

Category: Bloodbank

114. What is the component of choice for transfusion for a patient with Sickle cell anemia?

A. Washed RBCS

B. RBCs

C. Fresh frozen plasma

D. Cryoprecipitate

While D antigen is the most immunogenic, c antigen is the next Rh antigen to elicit immune response followed by E, C, and e

115 / 205

Category: Bloodbank

115. Which Rh antigen is the most immunogenic?

A. c

B. E

C. C

D. e

116 / 205

Category: Bloodbank

116. Individuals with hh genotype, anti-A, anti-B anti-A, B, and Anti-H are

A. Group O

B. Bombay phenotype

C. Group Jka

D. Chiedos Blood System

117 / 205

Category: Bloodbank

117. How many drop(s) of a patient serum is added in reverse blood typing?

A. 4 drops

B. 1 drop

C. 5 drops

D. 2 drops

118 / 205

Category: Bloodbank

118. What is the component of choice for transfusion for a patient with liver disease?

A. Irradiated RBCs

B. Fresh frozen plasma

C. Platelets

D. Granulocyte concentrates

119 / 205

Category: Bloodbank

119. Leukoreduced RBCs must contain less than______? Leukocytes and retain at least_____?

A. 5×10^10 and 90%

B. 5×10^6 and 85%

C. 5×10^11 and 85%

D. 5×10^6 and 75%

120 / 205

Category: Bloodbank

120. Which donor RBC unit should be selected first?

Anti-A	Anti- B	Anti- D	Rh control	A1 cell	B cell
4+	0	4+	0	0	4+

A. B positive

B. A positive

C. B negative

D. O negative

121 / 205

Category: Bloodbank

121. Kernicterus is caused by effect of?

A. Hypobilirubinemia

B. Hyperbilirubinemia

C. Anemia

D. Diabetes

Physical exam	Requirements	Physical exam	Requirements
Minimum Age	17 years Under 17 years needs parental consent	Blood pressure	180/100mmHg
Weight	110 Ibs	Pulse	50-100bpm
Hematocrit	38%	Temperature	99.5 ^OF (37.5^OC)
Hemoglobin (Women)	12.5g/dL	Hemoglobin (Men)	13.0g/dL

122 / 205

Category: Bloodbank

122. Which of the following would be cause for deferral for a male donor?

A. Temperature of 99.2 F

B. Hematocrit of 39%

C. Hemoglobin of 10.5g/dl

D. Blood pressure 180/90mm Hg

123 / 205

Category: Bloodbank

123. Agglutination cells form a cell layer at the top of the gel media. Grade the reaction.

A. 3+

B. 2+

C. 4+

D. 1+

E. Negative

124 / 205

Category: Bloodbank

124. What are the storage temperature and shelf life of pooled platelets?

A. Storage 20-24°C with rotation, expires 12 hours after pooling

B. Storage 20-24°C with rotation, expires 6 hours after pooling

C. Storage 20-28°C with rotation, expires 5 days after pooling

D. Storage 20-24°C, expires 4 hours after pooling

125 / 205

Category: Bloodbank

125. What are the required storage temperature and shelf life of thawed fresh frozen plasma (FFP)?

A. Storage -65°C, expires in 7 years

B. Storage -18°C, expires in 7 years

C. Storage 1-6°C, expires in 5 days

D. Storage -18°C, expires in 1 year

126 / 205

Category: Bloodbank

126. What antigens are present in a person with type B- blood?

A. A antigen

B. B antigens

C. AB antigens

D. None

127 / 205

Category: Bloodbank

127. What is the allowable shelf life of blood with CP2D anticoagulants?

A. 42 days

B. 35 days

C. 21 days

D. 24 days

128 / 205

Category: Bloodbank

128. Which of the following would be a cause permanent deferral?

A. Donor lived in UK for more than 3 months between 1980-1996

B. Recipient of human growth hormone

C. History of Chagas’ disease

D. All of the above

129 / 205

Category: Bloodbank

129. Transfusing one unit of RBC increases patient’s hematocrit by

A. 5%

B. 1%

C. 6%

D. 3%

Anti Jka is warm antibody; while others are cold reactive antibodies.

130 / 205

Category: Bloodbank

130. Which antibody does not fit with the others with respect to optimum phase of reactivity?

A. Anti M

B. Anti-P

C. Anti-I

D. Anti-Jka

131 / 205

Category: Bloodbank

131. A patient’s red blood cells gave the following reactions upon phenotyping. Which of the following is the most probable Rh genotype?

D	C		E		c		e
+		+		+		0		0

A. R2: DCe;

B. R1 : DcE

C. r’’: dce

D. r: dCE

132 / 205

Category: Bloodbank

132. What is the result of the ABO, Rh, and antibody screen test?

Anti-A	Anti- B	Anti- D	Rh	A1 cell	B cell
4+	4+	4+	0	0	0

Screening cell 1

Screening cell 2

Screening cell 3

A. Type AB, Rh positive, Antibody screen negative

B. Type AB, Rh positive, Antibody screen positive

C. Type 0, Rh negative, Antibody screen negative

D. Type 0, Rh negative, Antibody screen positive

133 / 205

Category: Bloodbank

133. What is the result of the ABO, Rh, and antibody screen test?

Anti-A	Anti- B	Anti- D	Rh	A1 cell	B cell
4+	0	0	0	0	4+

Screening cell 1

Screening cell 2

Screening cell 3

A. Type A, Rh positive, Antibody screen negative

B. Type B, Rh positive, Antibody screen positive

C. Type B, Rh negative, Antibody screen negative

D. Type A, Rh negative, Antibody screen negative

134 / 205

Category: Bloodbank

134. Which blood group system is associated with Chronic Granulomatous Disease (CGD)?

A. Anti P

B. Anti- Fya

C. Kell

D. Anti-Jkb

135 / 205

Category: Bloodbank

135. Which blood type is recommended by AABB Standards to be given to all weak-D recipients?

A. D-negative donor unit

B. D positive donor unit

C. Weak D donor unit

D. Partial D donor unit

Plasma hemoglobin, ammonia, and K+ levels increases

Plasma Na+, pH and 2,3-BPG levels decreases.

136 / 205

Category: Bloodbank

136. Biochemical changes occur during the shelf life of stored blood. Which of the following is a result of this “storage lesion”?

A. Increase in pH

B. Decrease in plasma K+

C. Decrease in plasma hemoglobin

D. Decrease in 2-3BPG levels

137 / 205

Category: Bloodbank

137. Rh antibodies react best at what temperature?

A. 4 deg. Celsuis

B. 37 deg. Celsuis

C. 24 deg. Celsuis

D. 18 deg. Celsuis

138 / 205

Category: Bloodbank

138. Which blood group system does Anti-Jk^a and Anti-Jk^b belong to?

A. Kell

B. Kidd

C. Duffy

D. Lutheran

Physical exam	Requirements	Physical exam	Requirements
Minimum Age	17 years Under 17 years needs parental consent	Blood pressure	180/100mmHg
Weight	110 Ibs	Pulse	50-100bpm
Hematocrit	38%	Temperature	99.5 ^OF (37.5^OC)
Hemoglobin (Women)	12.5g/dL	Hemoglobin (Men)	13.0g/dL

139 / 205

Category: Bloodbank

139. Which of the following would be cause for deferral for a female donor?

A. Temperature of 99.5 F

B. Hematocrit of 28%

C. Weighs 110Ibs

D. Blood pressure 130/70mm Hg

140 / 205

Category: Bloodbank

140. Rh antibodies is associated with which clinical condition?

A. Hemolytic disease of fetus and newborn

B. Addison disease

C. Stomatocytosis

D. Hemophilia

141 / 205

Category: Bloodbank

141. What type of immunoglobulin is anti-A,B?

A. IgM

B. IgA

C. IgG

D. IgE

Anti-P₁ is easily inhibited with P₁ substance(Hydatid cyst fluid)

142 / 205

Category: Bloodbank

142. Which antibody is neutralized by hydatid cyst fluid to allow detection of other antibodies?

A. Anti- Yta

B. Anti-Lu

C. Anti-I

D. Anti-P1

143 / 205

Category: Bloodbank

143. Use table below to answer this question. What type of antibody will blood type AB make?

Blood group

Antigen(s) on RBCS

Antibodies present in the serum

A and B

A. Anti-A

B. Anti-B

C. None

D. Anti-A,B

144 / 205

Category: Physics

144. A term used to describe the study of motion is called?

A. Velocity

B. Mechanics

C. Kinematics

D. Acceleration

145 / 205

Category: Bloodbank

145. The causative agent of Chagas disease is

A. Deer Fly

B. SandFly

C. Wuchereria bancrofti

D. Trypanosoma Cruzi

146 / 205

Category: Bloodbank

146. Which antigen is expressed when c and e are present on the same haplotype?

A. G antigen

B. f antigen

C. D antigen

D. E antigen

147 / 205

Category: Bloodbank

147. Which blood group system do Anti-Fy^a and Anti-Fy^bbelong to?

A. Kell

B. Kidd

C. Duffy

D. Lutheran

148 / 205

Category: Bloodbank

148. All cells pass through the gel media forming a cell button at the bottom of the microtube. Grade this gel reaction.

A. 3+

B. 2+

C. 4+

D. 1+

E. Negative

149 / 205

Category: Bloodbank

149. Which of the following RBC abnormality is associated with Rh null syndrome?

A. Spherocytosis

B. Granulocytosis

C. Stomatocytosis

D. Elliptocytosis

150 / 205

Category: Bloodbank

150. An ABO type on a patient gives the following reactions. What is the patient’s blood type?

Anti-A	Anti- B	Anti- D	Rh	A1 cell	B cell
4+	0	4+	0	0	3+

A. A positive

B. A negative

C. AB negative

D. O negative

151 / 205

Category: Bloodbank

151. The Rh systems genes are?

A. RHAG and RHD

B. RHD and RHCE

C. RHCE and RHRAG

Plasma hemoglobin, ammonia, and K+ levels increases

Plasma Na+, pH and 2,3-BPG levels decreases.

152 / 205

Category: Bloodbank

152. Biochemical changes occur during the shelf life of stored blood. Which of the following is a result of this “storage lesion”?

A. Decrease in pH

B. Decrease in plasma K+

C. Increase in plasma Na+

D. Decrease in plasma hemoglobin

153 / 205

Category: Coagulation

153. A hereditary thrombocytes disorder that is caused by lack of functional GPIb-IX-V complexes on the platelet surface, and is associated with presence of large platelets, increased MPV, decreased aggregation response to ristocetin, and normal vWF: RCo, vWF: Ag?

A. Von Williebrand disease

B. Bernard-Soulier syndrome

C. Glanzmann thrombasthenia

D. Hermansky-Pudlak syndrome

154 / 205

Category: Bloodbank

154. What is the component of choice for transfusion for a patient with neutropenia (<500 WBC/mm³)?

A. Fresh Frozen Plasma

B. Irradiated RBCs

C. Washed RBCs

D. Granulocyte concentrates

The genes GYPA codes for glycophorin A for blood group M and N

The genes GYPB codes for glycophorin B for blood group S and s

155 / 205

Category: Bloodbank

155. Which blood group system is produced by glycophorin A?

A. MNS

B. Ss

C. Lewis

D. MN

156 / 205

Category: Bloodbank

156. Which of the following are antibodies to low-frequency antigens?

A. Anti-Kpb

B. Anti-Jkb

C. Anti-Kpa and Anti Jsa

D. Anti-Kpb, Anti-Kpa and Anti Jsa

157 / 205

Category: Bloodbank

157. A patient’s red blood cells gave the following reactions upon phenotyping. Which of the following is the most probable Rh genotype?

A. DCe

B. DCE

C. dce

D. dCe

158 / 205

Category: Bloodbank

158. Solid button with clear background. Grade the reaction.

A. 3+

B. 4+

C. 1+

D. 2+

E. Negative

159 / 205

Category: Uncategorized

159. Transfusing one unit of RBC increases patient’s hemoglobin approximately by

A. 4 g/dL

B. 1 g/dL

C. 6 g/dL

D. 3 g/dL

160 / 205

Category: Bloodbank

160. Which donor RBC unit should be selected?

Anti-A	Anti- B	Anti- D	Rh control	A1 cell	B cell
4+	4+	0	0	0	0

A. O positive

B. AB positive

C. AB negative

D. O negative

161 / 205

Category: Bloodbank

161.

Which of the following potentiator cause agglutination by lowering zeta potential and increasing the rate of antibody uptake?

A. Polyethylene glycol

B. Low Ionic Strength Solution

C. Proteolytic Enzymes

D. Bovine Serum Albumin (BSA)

162 / 205

Category: Bloodbank

162. Predict the blood group using the information below.

Mom’s phenotype is group O, genotype OO

Dad’s phenotype is group O, genotype OO

A. 50% Group AO and 50% Group BO

B. 25% AB and 75% group B

C. 100% Group O

D. 50% Group AB and 50% Group O

163 / 205

Category: Bloodbank

163. Which Rh phenotype is written as D- – or -D- ?

A. Weak D

B. Rh null

C. D deletion

D. Partial D

164 / 205

Category: Bloodbank

164. Which autoantibody is associated with early abortion?

A. Kell

B. Kidd

C. anti-PP1pk

D. anti-PP1pk and anti-P

165 / 205

Category: Bloodbank

165. What are the four main blood groups in the ABO blood group system?

A. Group A, B, C, AB

B. Group A, B, O, AB

C. Group A, B, D, AB

D. Group A, O,B, AD

166 / 205

Category: Bloodbank

166. Rh antigens are proteins, unlike ABO antigens which are glycolipids.

A. False

B. True

167 / 205

Category: Bloodbank

167. What is the component of choice for transfusion for a patient with Fibrinogen deficiency?

A. Irradiated RBCs

B. Fresh Frozen Plasma

C. Cryoprecipitated Antihemophilic Factor

D. Thawed Plasma

168 / 205

Category: Bloodbank

168. Which donor RBC unit should be selected?

Anti-A

Anti- B

Anti- D

Rh control

A1 cell

B cell

A. A positive

B. O positive

C. AB Positive

D. B positive

169 / 205

Category: Bloodbank

169. Predict the blood group using the information below.

Mom’s phenotype is group B, genotype BO

Dad’s phenotype is group O, genotype OO

A. 50% Group B and 50% Group B

B. 25% AB and 75% group B

C. 100% AB

D. 50% Group B and 50% Group O

170 / 205

Category: Bloodbank

170. What is the patient’s ABO, Rh, and antibody screen?

Anti-A	Anti- B	Anti- D	Rh	A1 cell	B cell
0	0	0	0	4+	3+

Screening cell 1

Screening cell 2

Screening cell 3

A. Type AB, Rh positive, Antibody screen negative

B. Type O, Rh positive, Antibody screen positive

C. Type 0, Rh negative, Antibody screen negative

D. Type AB, Rh negative, Antibody screen negative

171 / 205

Category: Bloodbank

171. Which of the following antibody is an IgG biphasic antibody in Donath-Landsteiner antibody test?

A. Anti- Yta

B. Anti-Lu

C. Anti-P1

D. Lewis

172 / 205

Category: Bloodbank

172. What is the patient’s ABO, Rh, and antibody screen?

Anti-A	Anti- B	Anti- D	Rh	A1 cell	B cell
0	0	4+	0	4+	3+

Screening cell 1

Screening cell 2

Screening cell 3

A. Type AB, Rh positive, Antibody screen negative

B. Type O, Rh positive, Antibody screen positive

C. Type 0, Rh negative, Antibody screen positive

D. Type A, Rh negative, Antibody screen positive

173 / 205

Category: Bloodbank

173. Many small clumps with a cloudy background. Grade the reaction

A. 2+

B. 4+

C. 3+

D. 1+

E. Negative

174 / 205

Category: Bloodbank

174. For the following patient, indicate the component of choice for transfusion.

IgA deficient patient with anti-IgA antibodies

A. Washed RBCs

B. Irradiated RBCs

C. Fresh Frozen Plasma (FFP)

D. Cryoprecipitate

Plasma hemoglobin, ammonia, and K+ levels increases

Plasma Na+, pH and 2,3-BPG levels decreases.

175 / 205

Category: Bloodbank

175. Which autoantibody is associated with Echinococcus granulosis?

A. Kidd

B. Kell