Normocytic Normochromic Anemia -

This quiz will cover hereditary spherocytosis, Pyruvate kinase (PK) deficiency, Microangiopathic hemolytic anemias (MAHAs), Paroxysmal nocturnal hemoglobinuria (PNH), Hemolytic uremic syndrome (HUS), Thrombotic thrombocytopenic purpura (TTP), and Embden Meyerhof Pathway, Paroxysmal nocturnal hemoglobinuria (PNH), and G6PD deficiency

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Membranopathy and Enzymopathy

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Category: Hematology

1. Which of the following is an acquired membrane defect in which the red cell membrane has increased sensitivity for complement binding?

A. Pyruvate kinase (PK) deficiency

B. G6PD (glucose-6-phosphate dehydrogenase) deficiency

C. Hereditary spherocytosis

D. Paroxysmal nocturnal hemoglobinuria (PNH)

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Category: Hematology

2. Blood loss caused by gastrointestinal bleeding is classified as

A. Chronic blood loss

B. Reticulocytosis

C. Acute blood loss

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Category: Hematology

3. Which test is used to differentiate Warm autoimmune hemolytic anemia (WAIHA) from hereditary spherocytosis?

A. MCHC may be >37 g/dL

B. Increased osmotic fragility

C. Increased Bilirubin

D. Positive direct antiglobulin test (DAT)

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Category: Hematology

4. A sudden loss of blood from traumatic injuries is..

A. Chronic blood loss

B. Reticulocytosis

C. Acute blood loss

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Category: Hematology

5. Which hemolytic anemia is caused due to a deficiency of the enzyme ADAMTS 13?

A. Paroxysmal nocturnal hemoglobinuria (PNH)

B. Hemolytic uremic syndrome (HUS)

C. Microangiopathic hemolytic anemias (MAHAs)

D. Thrombotic thrombocytopenic purpura (TTP)uremic syndrome (HUS)

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Category: Hematology

6. Which hemolytic anemia occurs most often in children following E. coli infection?

A. Paroxysmal nocturnal hemoglobinuria (PNH)

B. Hemolytic uremic syndrome (HUS)

C. Microangiopathic hemolytic anemias (MAHAs)

D. Thrombotic thrombocytopenic purpura (TTP)

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Category: Hematology

7. Which of the following acquired hemolytic disorder causes intravascular hemolysis, presents with thrombocytopenia and schistocytes in peripheral blood smear?

A. Microangiopathic hemolytic anemias (MAHAs)

B. Paroxysmal nocturnal hemoglobinuria (PNH)

C. Hemolytic uremic syndrome (HUS)

D. Thrombotic thrombocytopenic purpura (TTP)

E. All of the above

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Category: Hematology

8. Which abnormal red blood cell is seen in abetalipoproteinemia?

A. Spherocytes

B. Acanthocytes

C. Echinocytes

D. Codocytes

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Category: Hematology

9. Which inclusion is seen in G6PD (glucose-6-phosphate dehydrogenase) deficiency?

A. Heinz bodies

B. Ringed sideroblasts

C. Howell jolly

D. Pappenheimer bodies

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Category: Hematology

10. In normocytic/normochromic anemia reticulocyte is

A. Increased

B. Decreased

C. Normal

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Category: Hematology

11. What is the most common enzyme deficiency in Embden Meyerhof Pathway?

A. G6PD (glucose-6-phosphate dehydrogenase) deficiency

B. Hereditary spherocytosis

C. Pyruvate kinase (PK) deficiency

D. Paroxysmal nocturnal hemoglobinuria (PNH)

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Which hemolytic anemia occurs most often in children following E. coli infection?

Hemolytic uremic syndrome (HUS)

Which hemolytic anemia is caused due to a deficiency of the enzyme ADAMTS 13?

Thrombotic thrombocytopenic purpura (TTP)

Which test is used to differentiate Warm autoimmune hemolytic anemia (WAIHA) from hereditary spherocytosis?

Positive direct antiglobulin test (DAT)

An acquired membrane defect in which the red cell membrane has an increased sensitivity for complement binding?

Paroxysmal nocturnal hemoglobinuria (PNH)

Normocytic Normochromic Anemia

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