Microcytic Hypochromic Anemias

1. Calculate percent transferrin 

Serum iron is 22 μg/dL

 TIBC is 180 μg/dL

2. A 21-year-old woman complains to his physician of fatigue, dizziness, and craving for ice. Her results are as follows: 

Based on her laboratory result, what is the cause of anemia?

WBC 4.8 x 10^9/L 

RBC 3.75 x 10^12/L 

Hemoglobin 9.8 g/dL

Hematocrit 29%

MCV 77.3 fL

MCHC 33.8 g/dL

Serum iron and ferritin is decreased

Elevated total iron-binding capacity (TIBC) 

Blood smear shows microcytic hypochromic red blood cells

3. A 25-year-old woman complains to his physician of extreme fatigue. Her CBC results are as follows: 

The results of the CBC and iron studies, in this case, are most characteristic of?

4. Impaired release of storage iron due to increased hepcidin levels will result in ?

5. Which of the following is the major transport protein of iron ?

6. Which of the following characterizes anemia of chronic inflammation?

7. Total iron binding capacity (TIBC) measures 

8. Microcytic, hypochromic red cells are most often associated with impaired

9. Serum ferritin is an indirect measurement of 

10. Which of the following characterizes iron deficiency anemia?

11. Impaired DNA metabolism is characteristic of which type of anemia ?

12. A 27-year-old woman complains to his physician of pain and fatigue. Her results are as follows: 

WBC 5.4 x 10^9/L 

RBC 3.9 x 10^12/L 

Hemoglobin 8.2 g/dL

Hematocrit 28%

MCV 72 fL

MCHC 29.3 g/dL

ESR increased

Serum iron and total iron-binding capacity (TIBC) both decreased

Serum ferritin slightly elevated. 

Presence of Prussian-blue-stainable iron in bone marrow was also noted.

Based her laboratory result, what is the cause of anemia?

13. Defective nuclear maturation commonly results in the production of red cells that are ?

14. Which protein regulates iron homeostasis ?