Microcytic Hypochromic Anemias

1. Microcytic, hypochromic red cells are most often associated with impaired

2. Calculate percent transferrin 

Serum iron is 22 μg/dL

 TIBC is 180 μg/dL

3. Which of the following is the major transport protein of iron ?

4. Which of the following characterizes iron deficiency anemia?

5. Which of the following characterizes anemia of chronic inflammation?

6. A 25-year-old woman complains to his physician of extreme fatigue. Her CBC results are as follows: 

The results of the CBC and iron studies, in this case, are most characteristic of?

7. Serum ferritin is an indirect measurement of 

8. A 21-year-old woman complains to his physician of fatigue, dizziness, and craving for ice. Her results are as follows: 

Based on her laboratory result, what is the cause of anemia?

WBC 4.8 x 10^9/L 

RBC 3.75 x 10^12/L 

Hemoglobin 9.8 g/dL

Hematocrit 29%

MCV 77.3 fL

MCHC 33.8 g/dL

Serum iron and ferritin is decreased

Elevated total iron-binding capacity (TIBC) 

Blood smear shows microcytic hypochromic red blood cells

9. Impaired DNA metabolism is characteristic of which type of anemia ?

10. Defective nuclear maturation commonly results in the production of red cells that are ?

11. A 27-year-old woman complains to his physician of pain and fatigue. Her results are as follows: 

WBC 5.4 x 10^9/L 

RBC 3.9 x 10^12/L 

Hemoglobin 8.2 g/dL

Hematocrit 28%

MCV 72 fL

MCHC 29.3 g/dL

ESR increased

Serum iron and total iron-binding capacity (TIBC) both decreased

Serum ferritin slightly elevated. 

Presence of Prussian-blue-stainable iron in bone marrow was also noted.

Based her laboratory result, what is the cause of anemia?

12. Which protein regulates iron homeostasis ?

13. Impaired release of storage iron due to increased hepcidin levels will result in ?

14. Total iron binding capacity (TIBC) measures