Leukemia Classification and Cytochemical stains -

This quiz will cover different types of cytochemical stains and leukemia classifications. These cytochemical stains will be covered in this quiz; Nonspecific esterase stains, Specific esterase stain and Sudan Black, Myleoperoxidase stain, and Periodic acid-schiff stain

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Leukemia Classification Quiz

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Category: Hematology

1. World Health Organization (WHO) defines acute leukemia as?

A. >20% bone marrow blasts.

B. >30% bone marrow blasts.

C. >70% bone marrow blasts.

D. >50% bone marrow blasts.

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Category: Hematology

2. Granulocytic cells will stain positive in which of the following stains?

A. Myeloperoxidase (MPO), Sudan black B, and Specific esterase stain

B. Myeloperoxidase (MPO), Periodic acid-Schiff (PAS), and non- specific esterase stain

C. Periodic acid-Schiff (PAS) and Nonspecific esterase stains

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Category: Hematology

3. Which stain is useful in the diagnosis of erythroleukemia (FAB M6) and acute lymphoblastic leukemia?

A. Myeloperoxidase (MPO)

B. Periodic acid-Schiff (PAS)

C. Nonspecific esterase stains

D. Sudan Black

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Category: Hematology

4. Which cell type is predominant in acute lymphoblastic leukemia?

A. lymphoblasts

B. myeloblasts

C. granulocytes

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Category: Hematology

5. French-American-British (FAB) defines acute leukemia as?

A. >20% bone marrow blasts.

B. >30% bone marrow blasts.

C. >70% bone marrow blasts.

D. >50% bone marrow blasts.

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Category: Hematology

6. Lymphocytic cell stains negative in which of the following stains?

A. Myeloperoxidase (MPO) and Sudan black B

B. Myeloperoxidase (MPO) and Periodic acid-Schiff (PAS)

C. Periodic acid-Schiff (PAS) and Nonspecific esterase stains

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Category: Hematology

7. Which classification is based on cellular morphology and cytochemical stain results?

A. French-American-British (FAB)

B. World Health Organization (WHO)

C. Cancer Association Method

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Category: Hematology

8. Which classification for hematopoietic malignancy is the accepted standard for diagnosis?

A. French-American-British (FAB)

B. World Health Organization (WHO)

C. Cancer Association Method

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Category: Hematology

9. Which of the following stains are used to differentiate blasts of acute myelogenous leukemias (AMLs) from acute lymphoblastic leukemia (ALLs)?

A. Myeloperoxidase (MPO) and Sudan black B

B. Myeloperoxidase (MPO) and Periodic acid-Schiff (PAS)

C. Periodic acid-Schiff (PAS) and Nonspecific esterase stains

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Category: Hematology

10. Increased LAP score is seen in?

A. Chronic myelogenous leukemia (CML)

B. Paroxysmal nocturnal hemoglobinuria

C. Neutrophilic leukemoid reaction

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Category: Hematology

11. Auer rods will stain positive in which of the following stains?

A. Myeloperoxidase (MPO) and Sudan black B

B. Myeloperoxidase (MPO) and Periodic acid-Schiff (PAS)

C. Periodic acid-Schiff (PAS) and Nonspecific esterase stains

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Category: Hematology

12. Which of the following stain is used in the diagnosis of Hairy cell leukemia?

A. Periodic acid-Schiff (PAS)

B. Nonspecific esterase stains

C. Sudan Black

D. Tartrate-resistant acid phosphatase stain (TRAP)

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Category: Hematology

13. Which cell type is predominant in acute myelogeneous leukemia?

A. lymphoblasts

B. myeloblasts

C. lymphocytes

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Category: Hematology

14. Which of the following stains is used in distinguishing acute leukemias of myeloid origin from the monocytic origin?

A. Myeloperoxidase (MPO)

B. Periodic acid-Schiff (PAS)

C. Nonspecific esterase stains

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Category: Hematology

15. Which test is used to differentiate chronic myelogenous leukemia (CML) from a neutrophilic leukemoid reaction (NLR)?

A. Periodic acid-Schiff (PAS)

B. Nonspecific esterase stains

C. Sudan Black

D. Leukocyte alkaline phosphatase (LAP)

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Category: Hematology

16. Which of the following cell type will stain negative in Myeloperoxidase (MPO) stains?

A. Granulocytic cells

B. Auer rods stain

C. Lymphocytic cells

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Category: Hematology

17. Which stain is useful in the diagnosis of acute monocytic leukemia (FAB M5)?

A. Myeloperoxidase (MPO)

B. Periodic acid-Schiff (PAS)

C. Nonspecific esterase stains

D. Sudan Black

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QUIZ PREVIEW

Which cell type is predominant in acute myelogenous leukemia?

Myeloblasts

Which classification for hematopoietic malignancy is the accepted standard for diagnosis?

World Health Organization (WHO)

World Health Organization (WHO) defines acute leukemia as?

>20% bone marrow blasts.

Which of the following stains is used in distinguishing acute leukemias of myeloid origin from the monocytic origin?

Nonspecific esterase stains

Which stain is useful in the diagnosis of erythroleukemia (FAB M6) and acute lymphoblastic leukemia?

Periodic acid-Schiff (PAS)

Which stains are used to differentiate blasts of acute myelogenous leukemias (AMLs) from acute lymphoblastic leukemia (ALLs)?

Myeloperoxidase (MPO) and Sudan black B

Leukemia Classification and Cytochemical stains

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