Immunology Question Bank

This 64 multiple choice test bank will cover immune system, antinuclear antibodies, immunodeficiencies, and hypersensitivity reactions.
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Category: Immunology and Serology

1. Which hypersensitivity reaction will cause a delayed immune response?

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Category: Immunology and Serology

2. What is the gene defect in Wiskott – Aldrich syndrome?

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Category: Immunology and Serology

3. Which type of immunity is acquired when maternal antibody crosses the placenta to an infant?

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Category: Immunology and Serology

4. What are the 2 types of light chain found in antibodies?

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Category: Immunology and Serology

5. Which immunoglobulin class is associated with type I hypersensitivity reactions?

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Category: Immunology and Serology

6. What are antibodies directed against the Fc fragment of immunoglobulin G (IgG) called?

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Category: Immunology and Serology

7. Which hypersensitivity reaction is cell mediated?

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Category: Immunology and Serology

8. Which type of hypersensitivity is caused by immune complex deposition on tissues?

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Category: Immunology and Serology

9. Which hypersensitivity reactions are humoral mediated?

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Category: Immunology and Serology

10. Which type of immunity lasts for life?

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Category: Immunology and Serology

11. Which compounds are most immunogenic?

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Category: Immunology and Serology

12. Which type of hypersensitivity is mediated by the antigen-antibody reaction?

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Category: Immunology and Serology

13. The portion of an antigen that binds to an antibody is called?

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Category: Immunology and Serology

14. Which of the following primary immunodeficiency is characterized by hypocalcemic tetany, due to underdevelopment of the thymus.

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Category: Immunology and Serology

15. What are molecules that trigger a hypersensitivity reaction called?

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Category: Immunology and Serology

16. Which type of hypersensitivity reaction is a Tuberculin test?

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Category: Immunology and Serology

17. A type of immunity acquired after exposure to foreign organisms or molecules is?

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Category: Immunology and Serology

18. What type of antinuclear antibody is associated with Nucleolar pattern?

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Category: Immunology and Serology

19. Which of the following is part of the body’s second line of defense?

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Category: Immunology and Serology

20. Which of the following are characteristics of immunogenicity?

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Category: Immunology and Serology

21. Which type of hypersensitivity is associated with blood transfusion reaction?

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Category: Immunology and Serology

22. Which regions do antibodies primarily migrate to during protein electrophoresis?

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Category: Immunology and Serology

23. Which type of hypersensitivity is caused by Glomerulonephritis?

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Category: Immunology and Serology

24. What type of antinuclear antibody is associated with homogeneous pattern?

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Category: Immunology and Serology

25. The first antibody produced against an immunogen is?

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Category: Immunology and Serology

26. Which hypersensitivity reaction is classified as an anaphylactic reaction?

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Category: Immunology and Serology

27. A low-molecular-weight molecule that elicits an immune response only when attached to another molecule is called?

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Category: Immunology and Serology

28. Antibodies are composed of?

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Category: Immunology and Serology

29. What type of immunity do vaccinations provide?

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Category: Immunology and Serology

30. Which of the following immunoglobulin is the predominant antibody in human serum?

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Category: Immunology and Serology

31. Which type of immunity will Rhogam provide to women exposed to Rh-positive fetal blood during pregnancy?

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Category: Immunology and Serology

32. A compound that enhances and stimulates an immune response is?

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Category: Immunology and Serology

33. Which immunoglobulin is produced in both primary and secondary immune responses?

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Category: Immunology and Serology

34. Which of the following is the only immunoglobulin that can cross the placenta?

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Category: Immunology and Serology

35. Which type of hypersensitivity is poison oak?

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Category: Immunology and Serology

36. An immunoglobulin deficiency characterized by elevated serum IgM levels and decreased levels or absence of other serum immunoglobulins, resulting in susceptibility to bacterial infection?

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Category: Immunology and Serology

37. Which auto immune disorder causes inflammation of the salivary and lacrimal glands causing dryness of the mouth and eyes?

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Category: Immunology and Serology

38. Which of the following is part of the body’s second line of defense?

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Category: Immunology and Serology

39. Which of the following disorder affects cellular immunity?

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Category: Immunology and Serology

40. What type of antinuclear antibody is associated with mixed connective tissue disease (MCTD)?

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Category: Immunology and Serology

41. Which of the following disorder affects humoral immunity?

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Category: Immunology and Serology

42. The state of being able to defend the body against foreign organisms or molecules is?

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Category: Immunology and Serology

43. An inherited immunodeficiency disorder characterized by the absence of mature B cells, resulting in a marked deficiency of all classes of immunoglobulins?

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Category: Immunology and Serology

44. Which auto immune disease is associated with elevated freeT3, total T3 and decreased TSH?

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Category: Immunology and Serology

45. What is responsible for the specificity of each class of antibody?

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Category: Immunology and Serology

46. Oligoclonal bands in CSF on electrophoresis is indicative of?

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Category: Immunology and Serology

47. Which type of adaptive immunity is most effective against intracellular pathogens?

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Category: Immunology and Serology

48. What type of antinuclear antibody is associated with the Speckled pattern ?

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Category: Immunology and Serology

49. How many molecule(s) of IgM is required to activate the classical pathway of complement?

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Category: Immunology and Serology

50.  An immunoglobulin deficiency characterized by absence of serum and secretory IgA?

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Category: Immunology and Serology

51. Serum IgE levels are elevated in which hypersensitivity reaction?

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Category: Immunology and Serology

52. A primary immunodeficiency characterized by MHC class II deficiency?

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Category: Immunology and Serology

53. Which of the following is part of the body’s first line of defense?

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Category: Immunology and Serology

54. Which of the following cell is part of Humoral-mediated immunity?

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Category: Immunology and Serology

55. A hereditary condition characterized by progressive neurologic problems that lead to difficulty walking?

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Category: Immunology and Serology

56. Which type of adaptive immunity is most effective against extracellular pathogens?

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Category: Immunology and Serology

57. What are the five classes of immunoglobulin?

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Category: Immunology and Serology

58. Which type of antinuclear antibody is associated with Sjogren syndrome?

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Category: Immunology and Serology

59. Which compounds are most immunogenic?

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Category: Immunology and Serology

60. A type of immunity that one is born with is?

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Category: Immunology and Serology

61. What causes erythema and wheal formation in Type I Hypersensitivity?

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Category: Immunology and Serology

62. What are the two types of adaptive immunity? 

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Category: Immunology and Serology

63. Substances capable of inducing an immune response are?

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Category: Immunology and Serology

64. What are proteins that bind to antigens?

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