Leukemia Classification and Cytochemical stains -

This quiz will cover different types of cytochemical stains and leukemia classifications. These cytochemical stains will be covered in this quiz; Nonspecific esterase stains, Specific esterase stain and Sudan Black, Myleoperoxidase stain, and Periodic acid-schiff stain

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Leukemia Classification Quiz

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Category: Hematology

1. World Health Organization (WHO) defines acute leukemia as?

A. >20% bone marrow blasts.

B. >30% bone marrow blasts.

C. >70% bone marrow blasts.

D. >50% bone marrow blasts.

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Category: Hematology

2. Granulocytic cells will stain positive in which of the following stains?

A. Myeloperoxidase (MPO), Sudan black B, and Specific esterase stain

B. Myeloperoxidase (MPO), Periodic acid-Schiff (PAS), and non- specific esterase stain

C. Periodic acid-Schiff (PAS) and Nonspecific esterase stains

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Category: Hematology

3. Which stain is useful in the diagnosis of acute monocytic leukemia (FAB M5)?

A. Myeloperoxidase (MPO)

B. Periodic acid-Schiff (PAS)

C. Nonspecific esterase stains

D. Sudan Black

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Category: Hematology

4. Which of the following stain is used in the diagnosis of Hairy cell leukemia?

A. Periodic acid-Schiff (PAS)

B. Nonspecific esterase stains

C. Sudan Black

D. Tartrate-resistant acid phosphatase stain (TRAP)

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Category: Hematology

5. French-American-British (FAB) defines acute leukemia as?

A. >20% bone marrow blasts.

B. >30% bone marrow blasts.

C. >70% bone marrow blasts.

D. >50% bone marrow blasts.

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Category: Hematology

6. Lymphocytic cell stains negative in which of the following stains?

A. Myeloperoxidase (MPO) and Sudan black B

B. Myeloperoxidase (MPO) and Periodic acid-Schiff (PAS)

C. Periodic acid-Schiff (PAS) and Nonspecific esterase stains

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Category: Hematology

7. Which of the following stains is used in distinguishing acute leukemias of myeloid origin from the monocytic origin?

A. Myeloperoxidase (MPO)

B. Periodic acid-Schiff (PAS)

C. Nonspecific esterase stains

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Category: Hematology

8. Which of the following cell type will stain negative in Myeloperoxidase (MPO) stains?

A. Granulocytic cells

B. Auer rods stain

C. Lymphocytic cells

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Category: Hematology

9. Which cell type is predominant in acute myelogeneous leukemia?

A. lymphoblasts

B. myeloblasts

C. lymphocytes

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Category: Hematology

10. Which cell type is predominant in acute lymphoblastic leukemia?

A. lymphoblasts

B. myeloblasts

C. granulocytes

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Category: Hematology

11. Which of the following stains are used to differentiate blasts of acute myelogenous leukemias (AMLs) from acute lymphoblastic leukemia (ALLs)?

A. Myeloperoxidase (MPO) and Sudan black B

B. Myeloperoxidase (MPO) and Periodic acid-Schiff (PAS)

C. Periodic acid-Schiff (PAS) and Nonspecific esterase stains

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Category: Hematology

12. Which classification is based on cellular morphology and cytochemical stain results?

A. French-American-British (FAB)

B. World Health Organization (WHO)

C. Cancer Association Method

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Category: Hematology

13. Which stain is useful in the diagnosis of erythroleukemia (FAB M6) and acute lymphoblastic leukemia?

A. Myeloperoxidase (MPO)

B. Periodic acid-Schiff (PAS)

C. Nonspecific esterase stains

D. Sudan Black

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Category: Hematology

14. Increased LAP score is seen in?

A. Chronic myelogenous leukemia (CML)

B. Paroxysmal nocturnal hemoglobinuria

C. Neutrophilic leukemoid reaction

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Category: Hematology

15. Which classification for hematopoietic malignancy is the accepted standard for diagnosis?

A. French-American-British (FAB)

B. World Health Organization (WHO)

C. Cancer Association Method

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Category: Hematology

16. Auer rods will stain positive in which of the following stains?

A. Myeloperoxidase (MPO) and Sudan black B

B. Myeloperoxidase (MPO) and Periodic acid-Schiff (PAS)

C. Periodic acid-Schiff (PAS) and Nonspecific esterase stains

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Category: Hematology

17. Which test is used to differentiate chronic myelogenous leukemia (CML) from a neutrophilic leukemoid reaction (NLR)?

A. Periodic acid-Schiff (PAS)

B. Nonspecific esterase stains

C. Sudan Black

D. Leukocyte alkaline phosphatase (LAP)

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QUIZ PREVIEW

Which cell type is predominant in acute myelogenous leukemia?

Myeloblasts

Which classification for hematopoietic malignancy is the accepted standard for diagnosis?

World Health Organization (WHO)

World Health Organization (WHO) defines acute leukemia as?

>20% bone marrow blasts.

Which of the following stains is used in distinguishing acute leukemias of myeloid origin from the monocytic origin?

Nonspecific esterase stains

Which stain is useful in the diagnosis of erythroleukemia (FAB M6) and acute lymphoblastic leukemia?

Periodic acid-Schiff (PAS)

Which stains are used to differentiate blasts of acute myelogenous leukemias (AMLs) from acute lymphoblastic leukemia (ALLs)?

Myeloperoxidase (MPO) and Sudan black B

Leukemia Classification and Cytochemical stains

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