Immunodeficiencies Quiz -

This quiz will cover Primary Immune Deficiencies, Humoral immune deficiencies, Selective IgA deficiency, Ataxia-telangiectasia, Hyper-IgM syndrome, Bruton X-linked agammaglobulinemia, Wiskott-Aldrich syndrome, DiGeorge syndrome, and Transient hypogammaglobulinemia of infancy

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Immunology

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Category: Immunology and Serology

1. Which of the following primary immunodeficiency is characterized by hypocalcemic tetany, due to underdevelopment of the thymus.

A. DiGeorge syndrome

B. Severe combined immune deficiency

C. Bare lymphocyte syndrome

D. Ataxia-telangiectasia

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Category: Immunology and Serology

2. A primary immunodeficiency characterized by MHC class II deficiency?

A. Severe combined immune deficiency

B. Bare lymphocyte syndrome

C. Ataxia-telangiectasia

D. Bare lymphocyte syndrome

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Category: Immunology and Serology

3. An immunoglobulin deficiency characterized by elevated serum IgM levels and decreased levels or absence of other serum immunoglobulins, resulting in susceptibility to bacterial infection?

A. Bruton X-linked agammaglobulinemia

B. Wiskott-Aldrich syndrome

C. DiGeorge syndrome

D. Hyper-IgM syndrome

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Category: Immunology and Serology

4. A hereditary condition characterized by progressive neurologic problems that lead to difficulty walking?

A. Selective IgA deficiency

B. Wiskott-Aldrich syndrome

C. DiGeorge syndrome

D. Ataxia-telangiectasia

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Category: Immunology and Serology

5. Which of the following disorder affects cellular immunity?

A. Selective IgA deficiency

B. Wiskott-Aldrich syndrome

C. DiGeorge syndrome

D. Ataxia-telangiectasia

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Category: Immunology and Serology

6. What is the gene defect in Wiskott – Aldrich syndrome?

A. Lyst gene

B. WASP gene

C. Wiskott gene

D. ADAMT-13

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Category: Immunology and Serology

7. An immunoglobulin deficiency characterized by absence of serum and secretory IgA?

A. Selective IgA deficiency

B. Wiskott-Aldrich syndrome

C. DiGeorge syndrome

D. Hyper-IgM syndrome

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Category: Immunology and Serology

8. An inherited immunodeficiency disorder characterized by the absence of mature B cells, resulting in a marked deficiency of all classes of immunoglobulins?

A. Bruton X-linked agammaglobulinemia

B. Wiskott-Aldrich syndrome

C. DiGeorge syndrome

D. Hyper-IgM syndrome

9 / 9

Category: Immunology and Serology

9. Which of the following disorder affects humoral immunity?

A. Selective IgA deficiency

B. Ataxia-telangiectasia

C. Bruton X-linked agammaglobulinemia

D. All of the Above

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An inherited immunodeficiency disorder characterized by the absence of mature B cells, resulting in a marked deficiency of all classes of immunoglobulins and recurrent infections?

Bruton X-linked agammaglobulinemia

An immunologlobulin deficiency characterized by the absence of serum and secretory IgA

Selective IgA deficiency

A primary immunodeficiency characterized by hypocalcemic tetany due to underdevelopment of the thymus is

DiGeorge syndrome

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