Immunology Question Bank Leave a Comment / By quizshell / January 7, 2022 This 64 multiple choice test bank will cover immune system, antinuclear antibodies, immunodeficiencies, and hypersensitivity reactions. 12345678910111213141516171819202122232425262728293031323334353637383940414243444546474849505152535455565758596061626364 0% 0 votes, 0 avg 12 GOOD LUCK WELL DONE 1 / 64 Category: Immunology and Serology 1. What is responsible for the specificity of each class of antibody? A. Variable domain B. Constant domain C. Epitope 2 / 64 Category: Immunology and Serology 2. What type of antinuclear antibody is associated with mixed connective tissue disease (MCTD)? A. Anti-Sm B. Anti-RNP antibody C. Anti-DNA D. A and B 3 / 64 Category: Immunology and Serology 3. What are proteins that bind to antigens? A. Albumin B. Antibody C. Haptogloblin D. Ceruplasmin 4 / 64 Category: Immunology and Serology 4. What is the gene defect in Wiskott - Aldrich syndrome? A. Lyst gene B. WASP gene C. Wiskott gene D. ADAMT-13 5 / 64 Category: Immunology and Serology 5. What causes erythema and wheal formation in Type I Hypersensitivity? A. Histamine B. Prostaglandins C. Leukotrienes D. Epinephrine 6 / 64 Category: Immunology and Serology 6. Which hypersensitivity reactions are humoral mediated? A. Type II Hypersensitivity B. Type I Hypersensitivity C. Type III Hypersensitivity D. All of the Above 7 / 64 Category: Immunology and Serology 7. Which of the following are characteristics of immunogenicity? A. Foreignness B. Route of entry C. Dose of immunogen D. All of the above 8 / 64 Category: Immunology and Serology 8. Which auto immune disorder causes inflammation of the salivary and lacrimal glands causing dryness of the mouth and eyes? A. Sjogren syndrome B. Hashimoto disease C. Mixed connective tissue disease (MCTD) D. Systemic lupus erythematosus 9 / 64 Category: Immunology and Serology 9. Which of the following disorder affects humoral immunity? A. Selective IgA deficiency B. Ataxia-telangiectasia C. Bruton X-linked agammaglobulinemia D. All of the Above 10 / 64 Category: Immunology and Serology 10. Which type of hypersensitivity is caused by immune complex deposition on tissues? A. Type II Hypersensitivity B. Type I Hypersensitivity C. Type IIl Hypersensitivity D. Type IV Hypersensitivity 11 / 64 Category: Immunology and Serology 11. What are molecules that trigger a hypersensitivity reaction called? A. Immunogenic B. Allergen C. Pollens D. Haptens 12 / 64 Category: Immunology and Serology 12. Which of the following is part of the body’s second line of defense? A. Epithelial cells B. Skin C. Mucus D. Complement system 13 / 64 Category: Immunology and Serology 13. Which compounds are most immunogenic? A. Lipids B. Nucleic acids C. Carbohydrates 14 / 64 Category: Immunology and Serology 14. What are the five classes of immunoglobulin? A. IgG, IgM, IgS, IgA, and IgD B. IgG, IgM, IgE, IgA, and IgB C. IgG, IgM, IgE, IgA, and IgD 15 / 64 Category: Immunology and Serology 15. What type of immunity do vaccinations provide? A. Cellular immunity B. Active immunity C. Passive immunity 16 / 64 Category: Immunology and Serology 16. Which of the following is the only immunoglobulin that can cross the placenta? A. IgM B. IgG C. IgA D. IgE 17 / 64 Category: Immunology and Serology 17. Which type of hypersensitivity is poison oak? A. Type II Hypersensitivity B. Type I Hypersensitivity C. Type IIl Hypersensitivity D. Type IV Hypersensitivity 18 / 64 Category: Immunology and Serology 18. The first antibody produced against an immunogen is? A. IgM B. IgG C. IgA D. IgE 19 / 64 Category: Immunology and Serology 19. Which type of immunity will Rhogam provide to women exposed to Rh-positive fetal blood during pregnancy? A. Active immunity B. Passive immunity C. Secondary immunity 20 / 64 Category: Immunology and Serology 20. Which type of hypersensitivity is caused by Glomerulonephritis? A. Type II Hypersensitivity B. Type I Hypersensitivity C. Type IIl Hypersensitivity D. Type IV Hypersensitivity 21 / 64 Category: Immunology and Serology 21. An immunoglobulin deficiency characterized by elevated serum IgM levels and decreased levels or absence of other serum immunoglobulins, resulting in susceptibility to bacterial infection? A. Bruton X-linked agammaglobulinemia B. Wiskott-Aldrich syndrome C. DiGeorge syndrome D. Hyper-IgM syndrome 22 / 64 Category: Immunology and Serology 22. What are the two types of adaptive immunity? A. Primary and secondary B. Acquired and Innate C. Cellular and Humoral 23 / 64 Category: Immunology and Serology 23. Which auto immune disease is associated with elevated freeT3, total T3 and decreased TSH? A. Sjogren syndrome B. Hashimoto disease C. Mixed connective tissue disease (MCTD) D. Graves’ disease 24 / 64 Category: Immunology and Serology 24. Which hypersensitivity reaction is cell mediated? A. Type II Hypersensitivity B. Type IV C. Type I Hypersensitivity D. Type III Hypersensitivity 25 / 64 Category: Immunology and Serology 25. Oligoclonal bands in CSF on electrophoresis is indicative of? A. Multiple sclerosis B. Hypersensitivity C. Wiskott-Aldrich syndrome D. HIV 26 / 64 Category: Immunology and Serology 26. Serum IgE levels are elevated in which hypersensitivity reaction? A. Type II Hypersensitivity B. Type I Hypersensitivity C. Type III Hypersensitivity D. Type IV Hypersensitivity 27 / 64 Category: Immunology and Serology 27. The state of being able to defend the body against foreign organisms or molecules is? A. Immunology B. Immunity C. Immunology D. Attenuated 28 / 64 Category: Immunology and Serology 28. A type of immunity acquired after exposure to foreign organisms or molecules is? A. Innate B. Adaptive C. Secondary D. Primary 29 / 64 Category: Immunology and Serology 29. Which of the following immunoglobulin is the predominant antibody in human serum? A. IgM B. IgG C. IgA D. IgE 30 / 64 Category: Immunology and Serology 30. What type of antinuclear antibody is associated with Nucleolar pattern? A. Anti-RNP antibody B. Centromere antibody C. Anti-DNA D. Histones 31 / 64 Category: Immunology and Serology 31. Which type of adaptive immunity is most effective against intracellular pathogens? A. Primary B. Cellular mediated immunity C. Innate D. Humoral mediated immunity 32 / 64 Category: Immunology and Serology 32. Which type of immunity lasts for life? A. Active immunity B. Passive immunity C. Secondary immunity 33 / 64 Category: Immunology and Serology 33. How many molecule(s) of IgM is required to activate the classical pathway of complement? A. Six B. One C. Three D. Four 34 / 64 Category: Immunology and Serology 34. What type of antinuclear antibody is associated with homogeneous pattern? A. Anti-Sm B. Anti-RNP antibody C. Anti-DNA D. Centromere antibody 35 / 64 Category: Immunology and Serology 35. What type of antinuclear antibody is associated with the Speckled pattern ? A. Anti-Sm B. Anti-RNP antibody C. Anti-DNA D. A and B 36 / 64 Category: Immunology and Serology 36. An inherited immunodeficiency disorder characterized by the absence of mature B cells, resulting in a marked deficiency of all classes of immunoglobulins? A. Bruton X-linked agammaglobulinemia B. Wiskott-Aldrich syndrome C. DiGeorge syndrome D. Hyper-IgM syndrome 37 / 64 Category: Immunology and Serology 37. An immunoglobulin deficiency characterized by absence of serum and secretory IgA? A. Selective IgA deficiency B. Wiskott-Aldrich syndrome C. DiGeorge syndrome D. Hyper-IgM syndrome 38 / 64 Category: Immunology and Serology 38. Which of the following cell is part of Humoral-mediated immunity? A. Natural killer (NK) cells B. T helper cells C. Plasma cells D. Cytotoxic T lymphocytes 39 / 64 Category: Immunology and Serology 39. Substances capable of inducing an immune response are? A. Adjuvant B. Immunogen C. Activators D. Stimulators 40 / 64 Category: Immunology and Serology 40. Which immunoglobulin is produced in both primary and secondary immune responses? A. IgG B. IgA C. IgM D. IgE 41 / 64 Category: Immunology and Serology 41. Which hypersensitivity reaction will cause a delayed immune response? A. Type II Hypersensitivity B. Type IV C. Type I Hypersensitivity D. Type III Hypersensitivity 42 / 64 Category: Immunology and Serology 42. Which hypersensitivity reaction is classified as an anaphylactic reaction? A. Type II Hypersensitivity B. Type I Hypersensitivity C. Type III Hypersensitivity D. Type IV Hypersensitivity 43 / 64 Category: Immunology and Serology 43. What are the 2 types of light chain found in antibodies? A. Kappa and Epsilon B. IgM and IgG C. IgA and IgE D. Kappa and lambda 44 / 64 Category: Immunology and Serology 44. Which type of hypersensitivity reaction is a Tuberculin test? A. Type II Hypersensitivity B. Type I Hypersensitivity C. Type IIl Hypersensitivity D. Type IV Hypersensitivity 45 / 64 Category: Immunology and Serology 45. Which type of antinuclear antibody is associated with Sjogren syndrome? A. Anti-SSA B. Anti-DNA C. Anti-histone D. anti-SSA, and anti-SSB 46 / 64 Category: Immunology and Serology 46. A type of immunity that one is born with is? A. Innate B. Secondary C. Primary D. Adaptive 47 / 64 Category: Immunology and Serology 47. Which of the following primary immunodeficiency is characterized by hypocalcemic tetany, due to underdevelopment of the thymus. A. DiGeorge syndrome B. Severe combined immune deficiency C. Bare lymphocyte syndrome D. Ataxia-telangiectasia 48 / 64 Category: Immunology and Serology 48. Which type of hypersensitivity is mediated by the antigen-antibody reaction? A. Type II Hypersensitivity B. Type I Hypersensitivity C. Type IIl Hypersensitivity D. Type IV Hypersensitivity 49 / 64 Category: Immunology and Serology 49. Which type of immunity is acquired when maternal antibody crosses the placenta to an infant? A. Active immunity B. Passive immunity C. Secondary immunity 50 / 64 Category: Immunology and Serology 50. A low-molecular-weight molecule that elicits an immune response only when attached to another molecule is called? A. Stimulants B. Hapten C. Adjuvant D. Immunogen 51 / 64 Category: Immunology and Serology 51. Which of the following is part of the body’s second line of defense? A. Phagocytosis B. Epithelial cells C. Skin D. Mucus 52 / 64 Category: Immunology and Serology 52. What are antibodies directed against the Fc fragment of immunoglobulin G (IgG) called? A. Gout Factor B. IgD C. IgA D. Rheumatoid factors (RFs) 53 / 64 Category: Immunology and Serology 53. Which regions do antibodies primarily migrate to during protein electrophoresis? A. Alpha and beta regions B. Beta and gamma regions C. Alpha and gamma regions D. Alpha and delta regions 54 / 64 Category: Immunology and Serology 54. Which type of hypersensitivity is associated with blood transfusion reaction? A. Type II Hypersensitivity B. Type I Hypersensitivity C. Type IIl Hypersensitivity D. Type IV Hypersensitivity 55 / 64 Category: Immunology and Serology 55. A primary immunodeficiency characterized by MHC class II deficiency? A. Severe combined immune deficiency B. Bare lymphocyte syndrome C. Ataxia-telangiectasia D. Bare lymphocyte syndrome 56 / 64 Category: Immunology and Serology 56. Which of the following is part of the body’s first line of defense? A. Epithelial cells B. White blood cells C. Complement system D. Natural killer (NK) cells 57 / 64 Category: Immunology and Serology 57. Which immunoglobulin class is associated with type I hypersensitivity reactions? A. IgG B. IgA C. IgM D. IgE 58 / 64 Category: Immunology and Serology 58. A hereditary condition characterized by progressive neurologic problems that lead to difficulty walking? A. Selective IgA deficiency B. Wiskott-Aldrich syndrome C. DiGeorge syndrome D. Ataxia-telangiectasia 59 / 64 Category: Immunology and Serology 59. Which type of adaptive immunity is most effective against extracellular pathogens? A. Primary B. Innate C. Cellular mediated immunity D. Humoral mediated immunity 60 / 64 Category: Immunology and Serology 60. A compound that enhances and stimulates an immune response is? A. Stimulants B. Hapten C. Adjuvant D. Immunogen 61 / 64 Category: Immunology and Serology 61. Antibodies are composed of? A. Two heavy chains and three light chains B. One heavy chain and two light chains C. Two heavy chains and two light chains D. Four heavy chains and four light chains 62 / 64 Category: Immunology and Serology 62. Which compounds are most immunogenic? A. Proteins B. Lipids C. Nucleic acids 63 / 64 Category: Immunology and Serology 63. Which of the following disorder affects cellular immunity? A. Selective IgA deficiency B. Wiskott-Aldrich syndrome C. DiGeorge syndrome D. Ataxia-telangiectasia 64 / 64 Category: Immunology and Serology 64. The portion of an antigen that binds to an antibody is called? A. Epitope B. Receptors C. Adjuvant D. Hapten Your score is LinkedIn Facebook Twitter VKontakte 0% Restart quiz Send feedback Click here For More Quizzes Share this: Share on X (Opens in new window) X Share on Facebook (Opens in new window) Facebook Like this:Like Loading...