224 Questions; Clinical Chemistry Question Banks

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224 Questions; Clinical Chemistry Question Banks

224 Multiple choice questions to help you prepare for the ASCP exam or quizzes.

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1.  What is the primary female sex hormone?

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2. In what condition would an increased level of serum albumin be expected?

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3. The serum concentration of electrolytes is quantified using

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4. Which enzyme is elevated in patient with alcoholic cirrhosis? 

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5. Which of the following electrolyte is an important buffer system of blood?

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6. Which of the following ion is a cation 

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7. Which of the following hormone stimulates lipolysis and  gluconeogenesis?

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8. In what form is glucose stored in muscle and liver?

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9. Which of the following is a sialylated Lewis blood group antigen associated with colorectal carcinoma?

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10. Which of the following protein is used to predict the risk of premature birth?

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11. Which of the following is an oncofetal antigen that is elevated in colorectal carcinoma?

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12. What is another name for Vitamin C?

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13. Which hormones stimulates uterine contractions during childbirth?

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14. What is the product of deamination of amino acids in the liver?

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15. What is a fasting blood glucose level >100 mg/dL called? 

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16. Which of the following condition causes respiratory acidosis?

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17. Which of the following ion is an anion 

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18. Which enzyme is elevated in acute pancreatitis? 

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19. What hormone increases osmolality?

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20. Which enzyme deficiency will result in increased sensitivity to  certain muscle relaxant drugs used during surgery? 

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21. What color does biuret turn when protein is present?

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22. Which protein transports iron?

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23. Which of the following compound is used to assess the glomerular filtration rate (GFR). 

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24. Which hormone Stimulates secretion of prolactin 

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25. Elevated levels of which lipoprotein is associated with increased risk for  atherosclerosis?

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26. Cushing syndrome causes?  

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27. Which ions is the major anion of extracellular fluid?

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28. Which of the following is an oncofetal antigen that is elevated in neural defect?

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29. What is the building block of proteins?

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30. Which lipoprotein is the primary carrier of cholesterol?

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31. Which enzyme is elevated in Mumps? 

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32. Which substance is released when serum calcium level increases?

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33. What is the process by which glycogen is broken down to glucose?

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34. Which lipoprotein function has an antiatherogenic effect?

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35. What is the major constituents of cell membranes and outer shells of  lipoprotein molecules? 

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36. Which lipoprotein is the largest and have lowest density? 

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37. Elevated alpha-1-fetoprotein during pregnancy is expected in which of the following condition(s)?

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38. Which type of specimen is used for Creatinine clearance test?

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39. Which type of lipid consists of one glycerol molecule and two fatty acid  molecules attached via ester bonds?

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40. Which analyte will be falsely elevated due to hemolysis?

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41. Which of the following condition will cause hyponatremia?

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42. Which of the following hormones does not promote an increase in blood  glucose levels? 

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43. Which of the following vitamin is fat-soluble?

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44. Scurvy is caused by a deficiency in which of the following?

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45.  In gout, which of the following compound deposits in joints and other body tissues? 

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46. Which of the following disorder is associated with an elevated blood ammonia level? 

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47. What is the presence of glucose in urine called? 

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48. Which hormones secreted by the anterior pituitary raises blood glucose  levels?

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49. Which lipoprotein are recycled chylomicron and VLDL molecules?

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50. Night blindness is caused by a deficiency in which of the following?

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51. Which of the immunoglobulin class is able to cross the placenta from the mother to the fetus? 

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52. What is the measure of the number of dissolved particles in solution expressed as osmoles per kilogram of water?

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53. What is the major constituents of cell membranes and outer shells of  lipoprotein molecules?

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54. Which of the following vitamin is water-soluble?

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55. Which type of lipid consists of one glycerol molecule and two fatty acid  molecules attached via ester bonds?

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56. Excessive galactose in blood and excretion in urine is called

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57. What hormone helps regulate Phosphorus?

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58. Which disorder is associated with Thiamin deficiency?

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59. Which exhibit diurnal variation, with highest levels in the morning?

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60. What type of diabetes is more prone to ketoacidosis? 

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61. Which enzyme is decreased in insecticide poisonings? 

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62. In diabetic ketoacidosis, total carbon dioxide is

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63. What molecule is formed from one molecule of glycerol and three fatty  acid molecules?

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64. Which hormone controls water homeostasis?

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65. Hemorrhagic disease is associated with deficiency of which of the following vitamin?

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66. What type of diabetes is more prone to ketoacidosis?

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67. Convert 20 mg/dL of urea nitrogen to urea. 

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68. Which hormone increases blood glucose during stress? 

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69. What is a fasting blood glucose level >100 mg/dL called?

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70. Which hormone increases blood glucose during stress?

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71. What is the process of formation of glycogen from glucose called?

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72. Which enzyme is elevated in prostate cancer? 

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73. Which of the following condition causes metabolic acidosis?

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74. Which of the following vitamin is fat-soluble?

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75. In which condition will antidiuretic hormone level decrease?

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76. Which disorder is associated with Vitamin B2 deficiency?

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77. Which hormone stimulates stimulates production of testosterone?

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78. What is the normal range of sodium?

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79. Which enzyme deficiency is associated with hemolytic anemia after  ingestion of fava beans? 

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80. Which of the following disorder is associated with an elevated serum uric level? 

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81. What molecule is formed from one molecule of glycerol and three fatty acid molecules?

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82. It is an indicator of arterial inflammation.  

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83. Which lipoprotein gives serum a turbid appearance? 

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84. In the diacetyl method, what does diacetyl react with to form a yellow product?

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85. Which of the following protein is elevated in the amniotic fluid in neural tube defects?

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86. Which disorder is characterized by buildup of unconjugated bilirubin in the blood due to deficiency of UDPglycuronyltransferase?

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87. Which hormone Stimulates secretion of follicle-stimulating hormone (FSH) ?

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88. Which disorder is associated with Niacin deficiency? 

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89. What form are carbohydrates stored in the liver and skeletal muscles?

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90.  Decreased alpha-1-fetoprotein level in maternal serum is expected in which of the following disorder?

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91. Which analyte should be placed on ice immediately after draw?

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92. What is another name for Vitamin B1?

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93. Given the following information for an average-size adult, calculate creatinine clearance. Urine creatinine—130 mg/dL Plasma creatinine—1.4 mg/dL Urine volume for 24 hours—1620 ml

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94. Which test is used to assess the average plasma glucose level that an  individual maintained during a previous 2- to 3-month period? 

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95. Which enzyme is elevated in Paget disease?

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96. What is the major waste product of purine catabolism? 

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97. Osteoporosis is caused by a deficiency in which of the following?

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98. Which of the following glycoprotein is elevated in trophoblastic tumors?

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99. Which of the following helps regulate calcium?

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100. The Kjeldahl tecnique for the determination of total proteim measures the amount of?

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101. Which hormone inhibits the secretion of Growth Hormone?

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102. Which of the following tumor marker is used for detecting recurrence of breast cancer?

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103. Which cardiac enzyme is elevated in central nervous system disorders? 

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104. The biuret method for the determination of protein concentrations measures the amount of?

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105. Which hormone inhibits the release of glucose from the liver?

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106. What vitamin helps regulate calcium?

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107. Which blood protein is most responsible for osmotic pressure?

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108. Of the following blood glucose levels, which would you expect to result  in glucose in the urine? 

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109. What is the major fat in adipose tissues? 

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110. What is renal threshold for glucose?

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111. What does hydrolysis of lactose yield? 

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112. Which enzyme is elevated in biliary tract obstruction? 

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113. What is the three-dimensional shape of a protein called?

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114. Which hormone regulates salt balance?

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115. The structure formed by the sequence of amino acids within a polypeptide chain is?

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116. Which type of diabetes is characterized by relative insulin resistance? 

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117. Which protein activates lecithincholesterol acyltransferase  (LCAT) and removes free cholesterol from extrahepatic tissues? 

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118. What does decreased pH and ctCO2 with normal PCO2 indicate? 

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119. What is the process by which glycogen is broken down to glucose? 

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120. In metabolic acidosis, a decreased pH triggers 

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121. Which lipoprotein is the largest and have lowest density? 

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122. Which of the following protein is found in urine of a patient with multiple myeloma?

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123. Which hormone inhibits the secretion of thyroid-stimulating hormone?

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124. Which of the following hormone stimulates lipolysis and  gluconeogenesis?

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125. Which test is used to assess the average plasma glucose level that an  individual maintained during a previous 2- to 3-month period? 

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126. Which of the following vitamin is water-soluble?

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127. A colored stool is seen in

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128. Cushing syndrome causes?  

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129. Which of the following condition causes respiratory alkalosis?

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130. What does increased ctCO2 and pH with normal PCO2 indicate? 

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131. Which of the following hormone is catecholamine?

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132. Which of the following immunoglobin is increased in allergies, asthma, and parasitic infections?

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133. What analyte is measured using the Jaffe reaction?

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134. Which hormone stimulates spermatogenesis?

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135. Which type of diabetes is characterized by relative insulin resistance?

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136. In metabolic acidosis, total carbon dioxide is

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137. What molecule is formed from one molecule of glycerol and three fatty  acid molecules? 

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138. Calculate LDL cholesterol given a total cholesterol of 220mg/dl,  65mg/dl of HDL and triglyceride 200 mg/dl 

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139. Which element distinguishes proteins from carbohydrate and lipid compounds?

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140. What is another name for Vitamin B6?

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141. Which disorder is associated with Vitamin B12 deficiency?

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142. Which hormone inhibits release of prolactin?

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143. What hormone helps regulate calcium?

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144. What is end product of glucose metabolism in anaerobic condition? 

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145. Which hormone inhibits secretion of insulin, glucagon, and growth  hormone?

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146. What form are carbohydrates stored in the liver and skeletal muscles?

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147. Which of the following conditions causes Hypocalcemia?

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148. What does normal ctCO2, increased pH with decreased PCO2 indicate? 

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149. What is the major protein found in Low-density lipoprotein (LDL)? 

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150. Which of the following vitamin is water-soluble?

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151. Which ions is the major cation of intracellular fluid?

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152. Which hormone inhibits the release of glucose from the liver?

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153. Which of the following condition is associated with (XXY)?

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154. An onset of diabetes mellitus during pregnancy is known as 

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155. Which condition is caused by deficient secretion of bilirubin into the bile canaliculi?

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156. Decreased level of haptoglobin is indicative of?

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157. What are positively charged ions called?

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158. What is the process of breaking down glucose to form pyruvate  molecules?

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159.  The Kjeldahl technique for the determination of serum total protein measures the amount of?

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160. Which hormone increases blood glucose by stimulating glycogenolysis?

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161. Excessive galactose in blood and excretion in urine is called

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162. Which of the following carbohydrates is a monosaccharide? 

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163. What is the final product of Epinephrine metabolism is?.

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164. Elevated levels of which lipoprotein is associated with decreased risk for  coronary artery disease?

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165. What is another name for Vitamin B2?

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166. What is the major fat in adipose tissues? 

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167. High-sensitivity CRP (hs-CRP) of 3.0 mg/L is indicative of  

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168. A waste product of muscle contraction that is formed from phosphocreatine is

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169. What is the renal threshold for glucose? 

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170. Given the following information for an average-size adult, calculate creatinine clearance. Urine creatinine—110 mg/dL Plasma creatinine—1.2 mg/dL Urine volume for 24 hours—1420 ml

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171. What compound is the major nitrogen-containing compound in the blood?

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172. Which of the following is a tissue-specific marker used to detect prostate cancer?

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173. Where is insulin produced?

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174. Triglycerides are transported through the body by 

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175. Which of the following lipid act as a precursor of bile acids, Vitamin D and  steroids?

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176. Which of the following oncofetal antigen is associated with Down syndrome?

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177. Decreased levels of which lipoprotein is associated with increased risk  for coronary artery disease?

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178. Which hormones secreted by the anterior pituitary raises blood glucose  levels?

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179. Which of the following carbohydrates is a polysaccharide? 

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180. Which hormones are secreted by the anterior Pituitary Gland?

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181. Which ions is the major cation of extracellular fluid?

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182. What is end product of glucose metabolism in anaerobic condition?

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183. What is the process by which glucose is formed from  noncarbohydrate sources?

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184. Where is insulin produced? 

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185. What are negatively charged ions called?

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186. What protein has the highest concentration in the plasma?

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187. In which condition would you expect an increased level of alpha-1-antitrypsin and C-reactive protein (CRP)?

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188. What type of diabetes is associated with obesity and sedentary lifestyle?

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189. Which of the following lipid act as a precursor of bile acids, Vitamin D and  steroids?

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190. Which marker is used as a predictor for cardiovascular risk; increased  levels seen in inflammation? 

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191. What does hydrolysis of lactose yield?  

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192. Which test is used to detect pregnancy?

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193. What is normal osmolal gap?

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194. Which enzyme is useful in forensic cases involving rape?

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195. Which disorder is associated with excess cortisol production?

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196. Which protein binds to free hemoglobin?

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197. Which glucose method is considered to be the reference method? 

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198. Which lipoprotein is the primary carrier of cholesterol?

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199. Which lipoprotein is known as "bad cholesterol"?

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200. What is another name for Vitamin B12?

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201. Which of the following vitamin is water-soluble?

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202. Rickets is caused by a deficiency in which of the following?

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203. What is the primary male sex hormone?

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204. An onset of diabetes mellitus during pregnancy is known as  

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205. In what condition would decreased level of alpha-1-antitrypsin be expected?

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206. Which of the following glycoprotein are markers for ovarian and endometrial cancer?

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207. Which of the following lipid act as a precursor of bile acids, Vitamin D and  steroids?

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208. Which one of the following biochemical marker is used for assessing  heart failure? 

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209. What is the presence of glucose in urine called? 

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210. Which lipoprotein is known as "Good cholesterol"?

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211. Elevated levels of which lipoprotein is associated with increased risk for  atherosclerosis?

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212. Which marker is used for the detection of colorectal cancer?

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213. Which lipoprotein is known as "bad cholesterol"?

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214. In metabolic alkalosis, bicarbonate is

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215. Triglycerides are transported through the body by 

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216. What is the process of formation of glycogen from glucose called? 

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217. Which lipoprotein is the largest and have lowest density?

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218. What type of diabetes is associated with obesity and a sedentary lifestyle? 

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219. Which hormone increases blood glucose by stimulating glycogenolysis? 

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220. What is the major protein found in High-density lipoprotein (HDL)? 

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221. What are macromolecules made of amino acids linked to another by peptide bond called?

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222. What is the process of breaking down glucose to form pyruvate  molecules?

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223. Which one of the following is the most specific biochemical marker of  myocardial infarction? 

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224. Which tumor marker is used for the detection of pancreatic cancer?

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